Intensity-modulated radiotherapy for cancers in childhood

被引:13
作者
Leseur, J. [2 ,3 ]
Carrie, C. [3 ]
Prise, E. Le [2 ]
Bernier, V. [4 ]
Beneyton, V. [3 ,5 ]
Mahe, M. A. [1 ]
Supiot, S. [1 ]
机构
[1] Ctr Rene Gauducheau, Dept Radiotherapie, Serv Radiotherapie, F-44800 Nantes, France
[2] Ctr Eugene Marquis, Serv Radiotherapie, F-35042 Rennes, France
[3] Ctr Leon Berard, Serv Radiotherapie, F-69373 Lyon 08, France
[4] Ctr Alexis Vautrin, Serv Radiotherapie, F-54500 Vandoeuvre Les Nancy, France
[5] Ctr Paul Strauss, Serv Radiotherapie, F-67000 Strasbourg, France
来源
CANCER RADIOTHERAPIE | 2009年 / 13卷 / 6-7期
关键词
IMRT; Pediatric tumors; Indications; Doses constraints; Tomotherapy; WHOLE-VENTRICULAR IRRADIATION; RADIATION-THERAPY; PEDIATRIC MEDULLOBLASTOMA; NASOPHARYNGEAL CARCINOMA; INTRACRANIAL GERMINOMA; NECK RHABDOMYOSARCOMA; CONFORMAL TECHNIQUES; HELICAL TOMOTHERAPY; DOSE CONSTRAINTS; RANDOMIZED-TRIAL;
D O I
10.1016/j.canrad.2009.07.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Approximately 40-50% of children with cancer will be irradiated during their treatment. Intensity-modulated radiotherapy (IMRT) by linear accelerator or helical tomotherapy improves dose distribution in target volumes and normal tissue sparing. This technology could be particularly useful for pediatric patients to achieve an optimal dose distribution in complex volumes close to critical structures. The use of IMRT can increase the volume of tissue receiving low-dose radiation, and consequently carcinogenicity in childhood population with a good overall survival and long period of life expectancy. This review will present the current and potential IMRT indications for cancers in childhood, and discuss the benefits and problems of this technology aiming to define recommendations in the use of IMRT and specific doses constraints in pediatry. (C) 2009 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:536 / 542
页数:7
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