EPIDEMIOLOGY AND ANTIBIOTIC RESISTANCE PROFILE OF BACTERIAL UROPATHOGENS IN MALE PATIENTS: A 10-YEAR RETROSPECTIVE STUDY

The purpose of our present study was to establish the incidence of UTIs in adult male patients in the Southern region of Hungary over a long surveillance period (2008 - 2017). The antimicrobial susceptibility testing was performed using the disk diffusion method. Overall, n = 3750 of these outpatient samples (17.73%) and n = 5902 of inpatient samples (30.54%) originated from male patients. Members of the Enterobacteriaceae family were the most commonly isolated (outpatient: 64.4%, inpatient: 55.57%), with E. coli being the most common urinary pathogen in male patients (outpatient: 37.23%, inpatient: 27.40%), followed by Enterococcus spp. (outpatient: 22.72%, inpatient: 23.43%), and P. aeruginosa (outpatient: 7.15%, inpatient: 9.2%). Between 2010 and 2017, n = 501 (62.65 +/- 13.51 per year) extended-spectrum beta-lactamase (ESBL) - positive isolates were recorded from outpatients and n = 737 (105.28 +/- 31.99 per year) from inpatients (p = 0.032). Similarly to other bacterial infections, patients affected by drug-resistant urinary pathogens may encounter a poor clinical outcome and complications.