The elevated markers of hypercoagulability in children with Henoch-Schonlein purpura

被引：36
作者：
Yilmaz, D
Kavakli, K
Ozkayin, N
机构：
[1] Ege Univ, Fac Med, Dept Pediat Hematol, Izmir, Turkey
[2] Ege Univ, Fac Med, Dept Pediat Nephrol, Izmir, Turkey
来源：
PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2005年 / 22卷 / 01期
关键词：
child; Henoch-Schonlein purpura; hypercoagulability;
D O I：
10.1080/08880010590896251
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Twenty-eight children with HSP and 79 healthy children were entered into study. Activities of protein C, free-protein S and antithrombin, activated protein C resistance, levels of fibrinogen. D-dimer, thrombin-antithrombin complex (TAT), prothrombin fragments 1 + 2 (PF1+2), and von Willrebrand factor antigen (vWAg) and its activity (RiCof) were investigated in acute and recovery phases of HSP and controls. Fibrinogen, D-dimer, TAT, PF1+2, vWAg, and RiCof levels in patients with HSP during the acute phase were significantly higher than those of recovery phase and of the controls. A significant correlation was detected between severity of disease and TAF, PF1+2, vWAg, and D-dimer levels.
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页码：41 / 48
页数：8
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