Updated international consensus report on the investigation and management of primary immune thrombocytopenia

被引：827

作者：

Provan, Drew ^{[1
]}

Arnold, Donald M. ^{[2
,3
,4
]}

Bussel, James B. ^{[5
]}

Chong, Beng H. ^{[6
]}

Cooper, Nichola ^{[7
]}

Gernsheimer, Terry ^{[8
]}

Ghanima, Waleed ^{[9
,10
,11
,12
]}

Godeau, Bertrand ^{[13
]}

Jose Gonzalez-Lopez, Tomas ^{[14
]}

Grainger, John ^{[15
]}

Hou, Ming ^{[16
]}

Kruse, Caroline ^{[17
]}

McDonald, Vickie ^{[18
]}

Michel, Marc ^{[13
]}

Newland, Adrian C. ^{[1
]}

Pavord, Sue ^{[19
]}

Rodeghiero, Francesco ^{[20
]}

Scully, Marie ^{[21
]}

Tomiyama, Yoshiaki ^{[22
]}

Wong, Raymond S. ^{[23
,24
]}

Zaja, Francesco ^{[25
]}

Kuter, David J. ^{[26
]}

机构：

[1] Queen Mary Univ London, Acad Haematol Unit, Barts & London Sch Med & Dent, Blizard Inst, London, England

[2] McMaster Univ, McMaster Ctr Transfus Res, Dept Med, Hamilton, ON, Canada

[3] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

[4] Canadian Blood Serv, Hamilton, ON, Canada

[5] Weill Cornell Med, Div Hematol Oncol, Dept Pediat, New York, NY USA

[6] Univ New South Wales, St George Hosp, NSW Hlth Pathol, Sydney, NSW, Australia

[7] Hammersmith Hosp, Dept Haematol, London, England

[8] Univ Washington, Seattle Canc Care Alliance, Seattle, WA 98195 USA

[9] Ostfold Hosp Trust, Dept Res, Gralum, Norway

[10] Ostfold Hosp Trust, Dept Med, Gralum, Norway

[11] Ostfold Hosp Trust, Dept Oncol, Gralum, Norway

[12] Univ Oslo, Inst Clin Med, Dept Hematol, Oslo, Norway

[13] Univ Paris Est Creteil, Ctr Reference Cytopenies Autoimmunes Adulte, Serv Med Interne, CHU Henri Mondor,AP HP, Creteil, France

[14] Hosp Univ Burgos, Dept Hematol, Burgos, Spain

[15] Royal Manchester Childrens Hosp, Dept Haematol, Manchester, Lancs, England

[16] Shandong Univ, Qilu Hosp, Dept Haematol, Jinan, Shandong, Peoples R China

[17] Platelet Disorder Support Assoc, Cleveland, OH USA

[18] Barts Hlth NHS Trust, Royal London Hosp, London, England

[19] Oxford Univ Hosp NHS Fdn Trust, Haematol Theme Oxford Biomed Res Ctr, Oxford, England

[20] San Bortolo Hosp, Hematol Project Fdn, Dept Cell Therapy & Hematol, Vicenza, Italy

[21] Univ Coll London Hosp, Dept Haematol, Cardiometab Programme NIHR UCLH UCL BRC, London, England

[22] Osaka Univ Hosp, Dept Blood Transfus, Osaka, Japan

[23] Chinese Univ Hong Kong, Prince Wales Hosp, Sir YK Pao Ctr Canc, Hong Kong, Peoples R China

[24] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Hong Kong, Peoples R China

[25] Azienda Sanitaria Univ Integrata, SC Ematol, Trieste, Italy

[26] Harvard Med Sch, Massachusetts Gen Hosp, Div Hematol, Boston, MA 02115 USA

来源：

BLOOD ADVANCES | 2019年 / 3卷 / 22期

关键词：

QUALITY-OF-LIFE; HIGH-DOSE DEXAMETHASONE; THROMBOPOIETIN-RECEPTOR AGONIST; ANTI-D IMMUNOGLOBULIN; LONG-TERM TREATMENT; BONE-MARROW EXAMINATION; FOLLOW-UP ANALYSIS; ADULT PATIENTS; INTRAVENOUS IMMUNOGLOBULIN; DOUBLE-BLIND;

D O I：

10.1182/bloodadvances.2019000812

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010. A critical review was performed to identify all relevant articles published between 2009 and 2018. An expert panel screened, reviewed, and graded the studies and formulated the updated consensus recommendations based on the new data. The final document provides consensus recommendations on the diagnosis and management of ITP in adults, during pregnancy, and in children, as well as quality-of-life considerations.

引用

页码：3780 / 3817

页数：38

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