Optimizing Nanohydroxyapatite Nanocomposites for Bone Tissue Engineering

被引：86
|
作者：
Lowe, Baboucarr [1 ]
Hardy, John G. [2 ,3 ]
Walsh, Laurence J. [1 ]
机构：
[1] Univ Queensland, Sch Dent, Brisbane, Qld 4006, Australia
[2] Univ Lancaster, Dept Chem, Lancaster LA1 4YB, England
[3] Univ Lancaster, Mat Sci Inst, Lancaster LA1 4YB, England
来源：
ACS OMEGA | 2020年 / 5卷 / 01期
关键词：
HYDROXYAPATITE-FUCOIDAN NANOCOMPOSITES; NANO-HYDROXYAPATITE; IN-VITRO; BIOMEDICAL APPLICATIONS; SCAFFOLDS; REGENERATION; HYDROGELS; BIOCOMPATIBILITY; NANOTECHNOLOGY; NANOMATERIALS;
D O I：
10.1021/acsomega.9b02917
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Bone tissue engineering involves the combined use of materials with functional properties to regenerate bone. Nanohydroxyapatite (nHA) can influence the behavior of cells. The functional and structural properties of nHA can be controlled during nanoparticle synthesis. This review defines the relationship between the attributes of nHA nanoparticles and their biological effects, focusing on biocompatibility, surface-area-to-volume ratio, bonding chemistry, and substrate functionality. The paper explores how these aspects have been applied in the development of scaffolds for the repair of damaged bone or regeneration of missing bone.
引用
收藏
页码：1 / 9
页数：9
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