Role of angiogenesis and angiogenic factors in colorectal cancer

被引：0
作者：
Balan, Barbara J. [1 ]
Slotwinski, Robert [1 ,3 ]
Skopinska-Rozewska, Ewa [2 ]
机构：
[1] Med Univ, Dept Immunol & Nutr, Warsaw, Poland
[2] Med Univ, Dept Pathol, Biostruct Ctr, Warsaw, Poland
[3] Polish Acad Sci, Dept Surg, Res Ctr, Warsaw, Poland
来源：
CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY | 2009年 / 34卷 / 04期
关键词：
colorectal cancer; angiogenesis; angiogenic factors; VEGF; ENDOTHELIAL GROWTH-FACTOR; TUMOR-CELL INVASION; COLON-CANCER; ORGANIZING PRINCIPLE; RECEPTOR; RECURRENCE; SURVIVAL; THERAPY; INHIBITORS; CARCINOMA;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Colorectal cancer, the second most frequent cause of death worldwide, is due to genetic changes in gastrointestinal cells Carcinogenesis depends on/is promoted/induced/initiated by/activation of oncogenes or inactivation of tumour suppressor genes. Microscopic human cancers may remain dormant for lifetime Tumor progression depends on a cascade of events during which the non-angiogenic phenotype switches to the angiogenic one. The switch promotes immediate recruitment of new blood vessel and, ultimately, tumor development.
引用
收藏
页码：254 / 260
页数：7
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