An experimental study of MRI-pathology comparison method for soft tissue tumors

PurposeTo explore an accurate radiologic-pathologic control method in soft tissue tumor.Materials and methodsFirst, we performed a preliminary experimental study of the radiologic-pathologic control method in soft tissue mass simulation model. Targeted localization markers were performed during MRI, surgery, and pathology, to ensure accurate correspondence between MRI slices and pathological sections. And the MRI image after printing was matched with the pathological material surface to obtain the pathological material corresponding to the region of interest (ROI). Second, we performed the same method on soft tissue tumor clinical research population. The long and short diameters of the tumor MRI slices and pathological sections were measured. A paired t test was used to assess differences between them.ResultA paired t test showed that there were no signifacant differences of the length and diameter of the simulation tumor measured between MRI slices and pathological sections in soft tissue tumor simulation model and clinical research population (p > 0.05).ConclusionThe "Body position line-MRI slice-Pathological section Five-step Control Method" created by this study could carry out a more accurate radiologic-pathologic comparison study in soft tissue tumors.