Cationic Three-component Coupling Involving an Optically Active Enamine Derivative. From Time Integration to Space Integration of Reactions

被引：184

作者：

Suga, Seiji ^{[1
]}

Yamada, Daisuke ^{[1
]}

Yoshida, Jun-ichi ^{[1
]}

机构：

[1] Kyoto Univ, Dept Synthet & Biol Chem, Grad Sch Engn, Nishikyo Ku, Kyoto 6158510, Japan

来源：

CHEMISTRY LETTERS | 2010年 / 39卷 / 04期

关键词：

ACYLIMINIUM ION POOLS; ORGANIC-SYNTHESIS; RADICAL-ADDITION; FLASH CHEMISTRY; GENERATION; CARBON; CYCLOADDITION; REDUCTION; TRANSFORMATIONS; EFFICIENCY;

D O I：

10.1246/cl.2010.404

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three-component coupling of an N-acyliminium cation pool, an optically active 2-t-butyloxazole derivative, and a carbon nucleophile such as allyltrimethylsilane was effectively achieved by a rapid one-pot method at -78 degrees C and a flow microreactor method at 0 degrees C.

引用

页码：404 / 406

页数：3

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