VARIANTS IN THE GENE GPBAR1 ENCODING THE BILE ACID RECEPTOR TGR5 DETERMINE PROGRESSION OF LIVER FIBROSIS IN PEDIATRIC AUTOIMMUNE LIVER DISEASE AND IN MURINE SCLEROSING CHOLANGITIS

被引：0

作者：

Matuschek, Nelson ^{[1
]}

Kudira, Ramesh ^{[2
]}

Mullen, Mary ^{[2
]}

Singh, Ruchi ^{[3
]}

Lam, Simon ^{[2
]}

Adachi, Senna ^{[2
]}

Maynor, Sean ^{[3
]}

Karns, Rebekah ^{[2
]}

Namjou, Bahram ^{[4
]}

Sheridan, Rachel M. ^{[5
]}

Miethke, Alexander G. ^{[2
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Pediat Gastroenterol, Cincinnati, OH 45229 USA

[2] Cincinnati Childrens Hosp Med Ctr, Div Pediat Gastroenterol Hepatol & Nutr, Cincinnati, OH 45229 USA

[3] Cincinnati Childrens Hosp Med Ctr, Gastroenterol Hepatol & Nutr, Cincinnati, OH 45229 USA

[4] Cchmc, CAGE, Cincinnati, OH USA

[5] Cincinnati Childrens Hosp Med Ctr, Div Pathol & Lab Med, Cincinnati, OH 45229 USA

来源：

HEPATOLOGY | 2019年 / 70卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

1413

引用

页码：854A / 855A

页数：2

共 32 条

[1] Role of TGR5 (GPBAR1) in Liver Disease
Keitel, Verena
Haeussinger, Dieter
SEMINARS IN LIVER DISEASE, 2018, 38 (04) : 333 - 339
[2] PROTECTIVE ROLE OF MEMBRANE BILE ACID RECEPTOR TGR5 (GPBAR1) IN DDC-INDUCED SCLEROSING CHOLANGITIS IN MICE
Baghdasaryan, A.
Jha, P.
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JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S197 - S198
[3] Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
Poole, D. P.
Godfrey, C.
Cattaruzza, F.
Cottrell, G. S.
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Pelayo, J. C.
Bunnett, N. W.
Corvera, C. U.
NEUROGASTROENTEROLOGY AND MOTILITY, 2010, 22 (07): : 814 - 825+e227
[4] The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver
Klindt, Caroline
Reich, Maria
Hellwig, Birte
Stindt, Jan
Rahnenfuehrer, Joerg
Hengstler, Jan G.
Koehrer, Karl
Schoonjans, Kristina
Haeussinger, Dieter
Keitel, Verena
CELLS, 2019, 8 (11)
[5] Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration
Verena Keitel
Maria Reich
Annika Sommerfeld
Stefanie Kluge
Ralf Kubitz
Dieter Häussinger
European Journal of Medical Research, 19
[6] Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration
Keitel, Verena
Reich, Maria
Sommerfeld, Annika
Kluge, Stefanie
Kubitz, Ralf
Haeussinger, Dieter
EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2014, 19
[7] 2-Phenoxy-nicotinamides are Potent Agonists at the Bile Acid Receptor GPBAR1 (TGR5)
Martin, Rainer E.
Bissantz, Caterina
Gavelle, Olivier
Kuratli, Christoph
Dehmlow, Henrietta
Richter, Hans G. F.
Sander, Ulrike Obst
Erickson, Shawn D.
Kim, Kyungjin
Pietranico-Cole, Sherrie Lynn
Alvarez-Sanchez, Ruben
Ullmer, Christoph
CHEMMEDCHEM, 2013, 8 (04) : 569 - 576
[8] THE BILE ACID RECEPTOR TGR5 IN ALCOHOLIC LIVER DISEASE
Pokhrel, Sabita
Dilts, Matthew
Stahl, Zachary
Boehme, Shannon
Chiang, John Y.
Ferrell, Jessica M.
HEPATOLOGY, 2022, 76 : S946 - S946
[9] GPBAR1/TGR5 Mediates Bile Acid-Induced Cytokine Expression in Murine Kupffer Cells
Lou, Guiyu
Ma, Xiaoxiao
Fu, Xianghui
Meng, Zhipeng
Zhang, Wenyu
Wang, Yan-Dong
Van Ness, Carl
Yu, Donna
Xu, Rongzhen
Huang, Wendong
PLOS ONE, 2014, 9 (04):
[10] ACTIVATION OF THE BILE ACID RECEPTOR TGR5 ON MACROPHAGES INDUCES TGFB SIGNALING AND PROMOTES FIBROSIS IN MURINE SCLEROSING CHOLANGITIS
Malik, Astha
Kudira, Ramesh
Bariya, Priya
Vagnozzi, Ronald J.
Pfuhler, Liva
Suhas, Pranathi
Matuschek, Nelson
Mullen, Mary
Miethke, Alexander
HEPATOLOGY, 2020, 72 : 123A - 123A

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