Short peptides containing L-lysine and ε-aminocaproic acid as potential plasmin inhibitors

被引：6

作者：

Purwin, M. ^{[1
]}

Bruzgo, I. ^{[1
]}

Markowska, A. ^{[1
]}

Midura-Nowaczek, K. ^{[1
]}

机构：

[1] Med Univ, Dept Organ Chem, Bialystok, Poland

来源：

PHARMAZIE | 2009年 / 64卷 / 11期

关键词：

SPECIFICITY; DIPEPTIDES;

D O I：

10.1691/ph.2009.9633

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Eight short pepticles containing L-lysine and epsilon-aminocaproic acid were obtained and their effect on the amidolytic activities of plasmin, thrombin and trypsin was examined. Tripeptide amide Boc-EACA-L-Lys-EACA-NH2 was the most effective and specific plasmin inhibitor.

引用

页码：765 / 767

页数：3

共 8 条

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