Manganese-Catalyzed Oxophosphorylation Reaction of Carbon-Carbon Double Bonds Using Molecular Oxygen in Air

被引：11

作者：

Yamamoto, Daisuke ^{[1
]}

Ansai, Hiromasa

Hoshino, Junichi

Makino, Kazuishi ^{[1
]}

机构：

[1] Kitasato Univ, Grad Sch Pharmaceut Sci, Lab Organ Chem Drug Dev, Minato Ku, Tokyo 1088641, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2018年 / 66卷 / 09期

基金：

日本学术振兴会;

关键词：

oxophosphorylation; atmospheric oxygen; manganese catalyst; beta-ketophosphonate; BETA-KETO PHOSPHONATES; DIRECT OXYPHOSPHORYLATION; H-PHOSPHONATES; AEROBIC OXYPHOSPHORYLATION; N-HYDROXYPHTHALIMIDE; CARBOXYLIC-ACIDS; OLEFIN SYNTHESIS; ALKENES; KETOPHOSPHONATES; ALKYNES;

D O I：

10.1248/cpb.c18-00381

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A novel aerobic manganese-catalyzed oxophosphorylation reaction of carbon-carbon double bonds of styrene derivatives and vinyl ethers using diethyl H-phosphonates was developed. This direct transformation of alkenes to beta-ketophosphonate readily proceeded at room temperature via the direct incorporation of molecular oxygen present in air (open flask).

引用

页码：873 / 879

页数：7