CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm

被引:15
作者
Qi, Han [1 ]
Zhang, Hao [2 ]
Wan, Chao [1 ]
Xie, Lin [1 ]
Song, Ze [1 ]
Fan, Weijun [1 ]
机构
[1] Sun Yat Sen Univ, Dept Imaging & Intervent Radiol, Collaborat Innovat Ctr Canc Med, Canc Ctr,State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China
[2] Qingdao Univ, Affiliated Hosp, Dept Intervent Med Ctr, Qingdao, Peoples R China
基金
中国国家自然科学基金;
关键词
CT-guidance; microwave ablation; liver tumor; diaphragm; treatment; PERCUTANEOUS RADIOFREQUENCY ABLATION; STAGE HEPATOCELLULAR-CARCINOMA; ARTIFICIAL PLEURAL EFFUSION; HEPATIC DOME; ETHANOL INJECTION; CANCER ADJACENT; GASTROINTESTINAL-TRACT; THERAPEUTIC-EFFICACY; COAGULATION THERAPY; PROGNOSTIC-FACTORS;
D O I
10.18632/oncotarget.17422
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. Results: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6 patients with ICRs achieved CRs after MWA. The CR rate for Group I was higher than Group H (99.0% vs. 80.0%, P=0.001).The mean follow-up time was 11.2 +/- 7.50 months. The total local recurrence (LR) rate was 15.3% (20/131). The complication rate was 26.5%, and no severe complications were recorded. All complications were controllable and treatable. The incidence of diaphragmatic thickening during the MWA was 18.8% (P>0.05); the incidence of exudative changes inside the lungs was 6.8% (P>0.05). Conclusions: CT-guided MWA can detect changes in liver tissue, in the diaphragm and nearby lung tissues during the ablation process. It's safe and effective to treat tumors close to the diaphragm by CT-guided MWA through the lung. Methods: CT-guided MWA was used on 131 tumors that were close to the diaphragm (distance between tumor and diaphragm 5 5 mm) in 117 patients with liver cancer. The tumors were divided into a < 3.0 cm group (Group I, n= 101) and a 3.0 cm group (Group II, n= 30) based on tumor diameters. The complications within 2 weeks following treatment were counted, and the safety and short-term efficacy of MWA were analyzed.
引用
收藏
页码:79270 / 79278
页数:9
相关论文
共 35 条
[11]   Diaphragmatic perforation and hernia after hepatic radiofrequency ablation [J].
Koda, M ;
Ueki, M ;
Maeda, N ;
Murawaki, Y .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (06) :1561-1562
[12]   Artificial ascites technique for percutaneous radiofrequency ablation of liver cancer adjacent to the gastrointestinal tract [J].
Kondo, Y. ;
Yoshida, H. ;
Shiina, S. ;
Tateishi, R. ;
Teratani, T. ;
Omata, M. .
BRITISH JOURNAL OF SURGERY, 2006, 93 (10) :1277-1282
[13]   Early-stage hepatocellular carcinoma in patients with cirrhosis: Long-term results of percutaneous image-guided radiofrequency ablation [J].
Lencioni, R ;
Cioni, D ;
Crocetti, L ;
Franchini, C ;
Della Pina, C ;
Lera, J ;
Bartolozzi, C .
RADIOLOGY, 2005, 234 (03) :961-967
[14]   Bile aspiration and hydrodissection to prevent complications in hepatic RFA close to the gallbladder [J].
Levit, Elena ;
Bruners, Philipp ;
Guenther, Rolf W. ;
Mahnken, Andreas H. .
ACTA RADIOLOGICA, 2012, 53 (09) :1045-1048
[15]   Percutaneous microwave ablation for liver cancer adjacent to the diaphragm [J].
Li, Meng ;
Yu, Xiaoling ;
Liang, Ping ;
Liu, Fangyi ;
Dong, Baowei ;
Zhou, Pei .
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2012, 28 (03) :218-226
[16]   Prognostic factors for survival in patients with hepatocellular carcinoma after percutaneous microwave ablation [J].
Liang, P ;
Dong, BW ;
Yu, XL ;
Yu, DJ ;
Wang, Y ;
Feng, L ;
Xiao, QJ .
RADIOLOGY, 2005, 235 (01) :299-307
[17]  
Liu Lin-Na, 2010, Chin J Cancer, V29, P830
[18]   Percutaneous Radiofrequency Ablation for Hepatic Tumors Abutting the Diaphragm: Clinical Assessment of the Heat-Sink Effect of Artificial Ascites [J].
Nam, Sang Yu ;
Rhim, Hyunchul ;
Kang, Tae Wook ;
Lee, Min Woo ;
Kim, Young-Sun ;
Choi, Dongil ;
Lee, Won Jae ;
Park, Yulri ;
Chang, Ilsoo ;
Lim, Hyo K. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2010, 194 (02) :W227-W231
[19]   Percutaneous microwave coagulation therapy with intraperitoneal saline infusion for hepatocellular carcinoma in the hepatic dome [J].
Ohmoto, K ;
Tsuzuki, M ;
Yamamoto, S .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1999, 172 (01) :65-66
[20]   Treatment of hepatocellular carcinoma by percutaneous tumor ablation methods: Ethanol injection therapy and radiofrequency ablation [J].
Omata, M ;
Tateishi, R ;
Yoshida, H ;
Shiina, S .
GASTROENTEROLOGY, 2004, 127 (05) :S159-S166