Pd(II)-Catalyzed C-H Activation/Aryl-Aryl Coupling of Phenol Esters

被引：353

作者：

Xiao, Bin ^{[1
]}

Fu, Yao ^{[1
]}

Xu, Jun ^{[1
]}

Gong, Tian-Jun ^{[1
]}

Dai, Jian-Jun ^{[1
]}

Yi, Jun ^{[1
]}

Liu, Lei ^{[2
]}

机构：

[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China

[2] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 02期

关键词：

CARBON-HYDROGEN BONDS; ONE-POT SYNTHESIS; ORTHO-ARYLATION; OXIDATIVE FUNCTIONALIZATION; ACIDS; SP(2); OXYGENATION; DERIVATIVES; REACTIVITY; COMPLEXES;

D O I：

10.1021/ja909818n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Although nitrogen-containing group-directed cyclopalladation reactions have been well-known, Pd(II) insertion into C-H bonds promoted by coordination of an oxygen-only group to the palladium remains rather rare. In the present study, the first cyclopalladation complex formed from a simple phenol ester was characterized by X-ray crystallography. A promising protocol for the ortho C-H activation/aryl-aryl Coupling of phenol esters that was not sensitive to moisture or air was then established. The utility of the reaction was demonstrated for the synthesis of useful phenol derivatives.

引用

页码：468 / +

页数：4

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