Bone marrow edema: definition, diagnostic value and prognostic value

被引:19
作者
Blum, A. [1 ]
Roch, D. [1 ]
Loeuille, D. [2 ]
Louis, M. [1 ]
Batch, T. [1 ]
Lecocq, S. [1 ]
Witte, Y. [1 ]
机构
[1] CHU Nancy, Hop Cent, Serv Imagerie Guilloz, F-54035 Nancy, France
[2] CHU Nancy, Hop Cent, Serv Rhumatol, F-54035 Nancy, France
来源
JOURNAL DE RADIOLOGIE | 2009年 / 90卷 / 12期
关键词
Bone marrow edema; Complex regional pain syndrome; MRI; Diffusion; Tumor; Scoring; Modic; Osteonecrosis; Anti-TNF alpha; Vertebroplasty; Chondroblastoma; Nidus; EARLY RHEUMATOID-ARTHRITIS; MR-IMAGING FINDINGS; ANTERIOR CRUCIATE LIGAMENT; VERTEBRAL END-PLATE; AGE-RELATED-CHANGES; LOW-BACK-PAIN; SPONDYLOARTHRITIS RESEARCH CONSORTIUM; INTERPRETATION PROMPTING REFERRALS; APPARENT DIFFUSION-COEFFICIENTS; CONTRAST-ENHANCED MRI;
D O I
10.1016/S0221-0363(09)73586-3
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Bone marrow edema is easily identified oil MRI. The terminology suggests that the water content of bone marrow is increased when it is T1W hypointense and T2W hyperintense. It is a misnomer since, histologically, the abnormality does not correspond to marrow edema. The histological findings vary based on the underlying etiology and the presence of Fibrosis or inflammatory infiltrate is frequent and often predominant. In France, this terminology is Used routinely to describe such lesions. The term osteitis is preferred to describe these marrow signal changes in the setting of rheumatic joint diseases. The detection of bone marrow edema is important because of its diagnostic and prognostic value. It occurs in isolation and is reversible in patients with bone contusion and complex regional pain syndrome. It indicates Underlying structural damage and may modify management in patients with rheumatoid arthritis or spondylarthropathies. MR scores for disease activity rely mainly oil the presence of marrow edema. Finally, diffusion weighted MR allows quantification of marrow edema and could be more sensitive than conventional MRI to detect inflammation. The purpose of this article is to review the imaging features of marrow edema, review the Underlying etiologies and its diagnostic and prognostic value.
引用
收藏
页码:1789 / 1811
页数:23
相关论文
共 176 条
[1]   SPONTANEOUS OSTEONECROSIS OF KNEE [J].
AHLBACK, S ;
BAUER, GCH ;
BOHNE, WH .
ARTHRITIS AND RHEUMATISM, 1968, 11 (06) :705-&
[2]   Modic changes, possible causes and relation to low back pain [J].
Albert, H. B. ;
Kjaer, P. ;
Jensen, T. S. ;
Sorensen, J. S. ;
Bendix, T. ;
Manniche, Claus .
MEDICAL HYPOTHESES, 2008, 70 (02) :361-368
[3]   From the RSNA refresher courses - Evaluation of the marrow space in the adult hip [J].
Andrews, CL .
RADIOGRAPHICS, 2000, 20 :S27-S42
[4]   Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis [J].
Appel, Heiner ;
Loddenkemper, Christoph ;
Grozdanovic, Zarko ;
Ebhardt, Harald ;
Dreimann, Marc ;
Hempfing, Axel ;
Stein, Harald ;
Metz-Stavenhagen, Peter ;
Rudwaleit, Martin ;
Sieper, Joachim .
ARTHRITIS RESEARCH & THERAPY, 2006, 8 (05)
[5]   MR and CT features of craniocervical junction tuberculosis: a report of 5 cases [J].
Augier, A. ;
Zrig, H. ;
Roqueplan, F. ;
Brauner, M. ;
Dumas, J. L. .
JOURNAL DE RADIOLOGIE, 2008, 89 (05) :585-589
[6]   Diagnostic value of apparent diffusion coefficients to differentiate benign from malignant vertebral bone marrow lesions [J].
Balliu, E. ;
Vilanova, J. C. ;
Pelaez, I. ;
Puig, J. ;
Remollo, S. ;
Barcelo, C. ;
Barcelo, J. ;
Pedraza, S. .
EUROPEAN JOURNAL OF RADIOLOGY, 2009, 69 (03) :560-566
[7]   Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-α antibody infliximab [J].
Baraliakos, X. ;
Listing, J. ;
Brandt, J. ;
Haibel, H. ;
Rudwaleit, M. ;
Sieper, J. ;
Braun, J. .
RHEUMATOLOGY, 2007, 46 (09) :1450-1453
[8]   The relationship between inflammation and new bone formation in patients with ankylosing spondylitis [J].
Baraliakos, Xenofon ;
Listing, Joachim ;
Rudwaleit, Martin ;
Sieper, Joachim ;
Braun, Juergen .
ARTHRITIS RESEARCH & THERAPY, 2008, 10 (05)
[9]   Quantitative analyses of sacroiliac biopsies in spondyloarthropathies: T cells and macro phages predominate in early and active sacroiliitis - cellularity correlates with the degree of enhancement detected by magnetic resonance imaging [J].
Bellow, M ;
Fischer, T ;
Reisshauer, H ;
Backhaus, M ;
Sieper, J ;
Hamm, B ;
Braun, J .
ANNALS OF THE RHEUMATIC DISEASES, 2000, 59 (02) :135-140
[10]   Severity of Baseline Magnetic Resonance Imaging-Evident Sacroiliitis and HLA-B27 Status in Early Inflammatory Back Pain Predict Radiographically Evident Ankylosing Spondylitis at Eight Years [J].
Bennett, A. N. ;
McGonagle, D. ;
O'Connor, P. ;
Hensor, E. M. A. ;
Sivera, F. ;
Coates, L. C. ;
Emery, P. ;
Marzo-Ortega, H. .
ARTHRITIS AND RHEUMATISM, 2008, 58 (11) :3413-3418