Synthesis and antimicrobial activity of 1-aryl-2-amino-3-(4-arylthiazol-2-yl)/(benzothiazol-2-yl)guanidines

被引：27
|
作者：
Lakhan, R [1 ]
Sharma, BP
Shukla, BN
机构：
[1] Banaras Hindu Univ, Dept Chem, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Inst Med Sci, Dept Microbiol, Varanasi 221005, Uttar Pradesh, India
来源：
FARMACO | 2000年 / 55卷 / 05期
关键词：
antimicrobial activity; minimum inhibitory concentration; guanidines;
D O I：
10.1016/S0014-827X(00)00032-X
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The synthesis of fifteen new 1-aryl-2-amino-3-(4-arylthiazol-2-yl)/(benzothiazol-2-yl)guanidines is described. They were screened for their antimicrobial susceptibility by the standard disc diffusion method of the World Health Organization (WHO) and the activities compared with that of standard strain of Escherichia coli NCTC 10418. The sensitive aminoguanidines were further subjected to the minimum inhibitory concentration (MIC) test. (C) 2000 Elsevier Science S.A. All rights reserved.
引用
收藏
页码：331 / 337
页数：7
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