Antitumor activity of lenvatinib against acquired resistance tumor to anti-VEGF therapy in mouse syngeneic tumor models

被引：0
|
作者：
Ichikawa, Kenji [1 ]
Miyano, Saori Watanabe [1 ]
Minoshima, Yukinori [1 ]
Matsui, Junji [1 ]
Funahashi, Yasuhiro [1 ]
机构：
[1] Eisai & Co Ltd, Tsukuba Res Labs, Tsukuba, Ibaraki, Japan
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-196
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
196
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Tumor refractoriness to anti-VEGF therapy
    Ribatti, Domenico
    ONCOTARGET, 2016, 7 (29) : 46668 - 46677
  • [2] Interaction of VEGF and Notch pathways in tumor angiogenesis: DLL4 contributes to tumor resistance to anti-VEGF therapy in preclinical models
    Li, Ji-Liang
    Sainson, Richard
    Oon, Chern
    Leek, Russell
    Turley, Helen
    Harrington, Laura
    Sheldon, Helen
    Bernhard, Eric
    Im, Jae
    Shi, Wen
    Harris, Adrian
    CANCER RESEARCH, 2009, 69
  • [3] Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy
    Ichikawa, Kenji
    Miyano, Saori Watanabe
    Minoshima, Yukinori
    Matsui, Junji
    Funahashi, Yasuhiro
    SCIENTIFIC REPORTS, 2020, 10 (01) : 2939
  • [4] Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy
    Kenji Ichikawa
    Saori Watanabe Miyano
    Yukinori Minoshima
    Junji Matsui
    Yasuhiro Funahashi
    Scientific Reports, 10
  • [5] MetMAb significantly enhances anti-tumor activity of anti-VEGF and/or erlotinib in several animal tumor models
    Mark, M.
    Zhang, Y.
    Su, Y.
    Romero, M. S.
    Severin, C.
    Zheng, Z.
    Mendoza, N.
    Kaufman, D. W.
    Woude, G. F. Vance
    Filvaroff, E.
    EJC SUPPLEMENTS, 2008, 6 (12): : 175 - 175
  • [6] Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments antitumor activity in melanoma
    Tran, Thuy T.
    Caulfield, Jasmine
    Zhang, Lin
    Schoenfeld, David
    Djureinovic, Dijana
    Chiang, Veronica L.
    Oria, Victor
    Weiss, Sarah A.
    Olino, Kelly
    Jilaveanu, Lucia B.
    Kluger, Harriet M.
    JCI INSIGHT, 2023, 8 (07)
  • [7] IL11 mediates tumor resistance to anti-VEGF therapy in lung cancer
    Li, Jie
    Xie, Kun
    Mei, Shenglin
    Xu, Yuanjian
    Gu, Hua
    Li, Dong
    Chen, Kaiming
    Tao, Fei
    Eerdeng, Jiya
    Fang, Jianmin
    CANCER RESEARCH, 2017, 77
  • [8] Tumor resistance to anti-VEGF therapy through up-regulation of VEGF-C expression
    Li, Dong
    Xie, Kun
    Ding, Guitao
    Li, Jie
    Chen, Kaiming
    Li, Hongwen
    Qian, Jie
    Jiang, Cizhong
    Fang, Jianmin
    CANCER LETTERS, 2014, 346 (01) : 45 - 52
  • [9] Tumor-Associated Fibroblasts as "Trojan Horse" Mediators of Resistance to Anti-VEGF Therapy
    Francia, Giulio
    Emmenegger, Urban
    Kerbel, Robert S.
    CANCER CELL, 2009, 15 (01) : 3 - 5
  • [10] Anti-VEGF Therapy in Breast and Lung Mouse Models of Cancers
    Marina, Di Domenico
    Carmela, Ricciardi
    Alfredo, Fusco
    Maria, Pierantoni Giovanna
    JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2011,
12345