Developing Pharmacogenomic Reports: Insights from Patients and Clinicians

被引：15

作者：

Jones, Laney K. ^{[1
]}

Rahm, Alanna Kulchak ^{[1
]}

Gionfriddo, Michael R. ^{[1
]}

Williams, Janet L. ^{[1
]}

Fan, Audrey L. ^{[1
,2
]}

Pulk, Rebecca A. ^{[1
]}

Wright, Eric A. ^{[1
]}

Williams, Marc S. ^{[1
]}

机构：

[1] Geisinger, Danville, PA 17822 USA

[2] Genome Med, San Francisco, CA USA

来源：

CTS-CLINICAL AND TRANSLATIONAL SCIENCE | 2018年 / 11卷 / 03期

关键词：

GENOMIC LABORATORY REPORTS; INVITING PATIENTS; DOCTORS NOTES; PHARMACISTS; ATTITUDES; VIEWS; READ;

D O I：

10.1111/cts.12534

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Increasingly, for a variety of indications, patients have their genomes sequenced and actionable results returned. A subset of returned results is pharmacogenomic (PGx) variants involved in the metabolism or action of medications. Although the impact of these variants on health is well-documented, little research exists on how to communicate these findings to patients and clinicians. We conducted semistructured interviews with end users to understand how best to communicate PGx results. Overall, patients and clinicians had similar opinions regarding report content, delivery, and application. Unique concerns specific to each stakeholder group were also expressed. Patients wanted an easy-to-understand individualized report that clinicians utilized to guide their care. Clinicians wanted reports that were easy-to-use, actionable, and integrated into their workflow. Implementation of these reports in a clinical setting will allow for broader user feedback and iterative improvement.

引用

页码：289 / 295

页数：7

共 26 条

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