Scaffolds based on biopolymeric foams

被引：121
作者：
Barbetta, A
Dentini, M
De Vecchis, MS
Filippini, P
Formisano, G
Caiazza, S
机构：
[1] Univ Roma La Sapienza, Dept Chem, I-00185 Rome, Italy
[2] Ist Super Sanita, Ultrastrutture Lab, I-00161 Rome, Italy
来源：
ADVANCED FUNCTIONAL MATERIALS | 2005年 / 15卷 / 01期
关键词：
D O I：
10.1002/adfm.200400072
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new approach for the preparation of hydrophilic and biocompatible porous scaffolds is described. The procedure involves the derivatization of a biopolymer by the introduction of vinylic moieties, formation of a high-internal-phase oil-in-water emulsion, and its subsequent polymerization. The ensuing materials are characterized by a highly porous morphology represented by pores completely interconnected by a plurality of holes. The hydrophilic and biocompatible nature of these materials make them good candidates for application as scaffolds for tissue engineering.
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页码：118 / 124
页数：7
相关论文
共 39 条
[1]  
AKAY G, 2000, Patent No. 0034454
[2]  
[Anonymous], 1997, CELLULAR SOLID STRUC
[3]   Morphology and surface area of emulsion-derived (PolyHIPE) solid foams prepared with oil-phase soluble porogenic solvents: Three-component surfactant system [J].
Barbetta, A ;
Cameron, NR .
MACROMOLECULES, 2004, 37 (09) :3202-3213
[4]  
BARBETTA A, 2003, Patent No. 2003A00307
[5]   Tissue engineering of human biliary epithelial cells on polyglycolic acid/polycaprolactone scaffolds maintains long-term phenotypic stability [J].
Barralet, JE ;
Wallace, LL ;
Strain, AJ .
TISSUE ENGINEERING, 2003, 9 (05) :1037-1045
[6]   Tissue engineering matrixes by emulsion templating [J].
Busby, W ;
Cameron, NR ;
Jahoda, ABC .
POLYMER INTERNATIONAL, 2002, 51 (10) :871-881
[7]   Emulsion-derived foams (PolyHIPEs) containing poly(ε-caprolactone) as matrixes for tissue engineering [J].
Busby, W ;
Cameron, NR ;
Jahoda, CAB .
BIOMACROMOLECULES, 2001, 2 (01) :154-164
[8]  
Cadée JA, 2000, J BIOMED MATER RES, V50, P397
[9]  
Crescenzi V, 2002, MACROMOL CHEM PHYSIC, V203, P1285, DOI 10.1002/1521-3935(200207)203:10/11<1285::AID-MACP1285>3.0.CO
[10]  
2-2
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