Large clinical trials in musculoskeletal trauma: Are they possible? Lessons learned from the international study of the use of rhBMP-2 in open tibial fractures

被引：20
作者：
Csimma, C
Swiontkowski, MF
机构：
[1] Wyeth Res, Cambridge, MA 02140 USA
[2] Univ Minnesota, Dept Orthopaed Surg, Minneapolis, MN 55454 USA
来源：
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME | 2005年 / 87A卷 / 01期
关键词：
D O I：
10.2106/JBJS.D.01938
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：218 / 222
页数：5
相关论文
共 4 条
  • [1] *COMM PROPR MED PR, 2001, POINTS CONS APPL MET, P99
  • [2] CSIMMA C, 2000, BRIT ORTH ASS JAP OR
  • [3] Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures -: A prospective, controlled, randomized study of four hundred and fifty patients
    Govender, S
    Csimma, C
    Genant, HK
    Valentin-Opran, A
    Amit, Y
    Arbel, R
    Aro, H
    Atar, D
    Bishay, M
    Börner, MG
    Chiron, P
    Choong, P
    Cinats, J
    Courtenay, B
    Feibel, R
    Geulette, B
    Gravel, C
    Haas, N
    Raschke, M
    Hammacher, E
    van der Velde, D
    Hardy, P
    Holt, M
    Josten, C
    Ketterl, RL
    Lindeque, B
    Lob, G
    Mathevon, H
    Mccoy, G
    Marsh, D
    Miller, R
    Munting, E
    Oevre, S
    Nordsletten, L
    Patel, A
    Pohl, A
    Rennie, W
    Reynders, P
    Rommens, PM
    Rondia, J
    Rossouw, WC
    Daneel, PJ
    Ruff, S
    Rüter, A
    Santavirta, S
    Schildhauer, TA
    Gekle, C
    Schnettler, R
    Segal, D
    Seiler, H
    [J]. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2002, 84A (12) : 2123 - 2134
  • [4] Type-II error rates (beta errors) of randomized trials in orthopaedic trauma
    Lochner, HV
    Bhandari, M
    Tornetta, P
    [J]. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2001, 83A (11) : 1650 - 1655
1