Characteristics of Hospitalized and Nonhospitalized Patients in a Nationwide Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injury - United States, November 2019

被引：59

作者：

Chatham-Stephens, Kevin ^{[1
]}

Roguski, Katherine ^{[2
]}

Jang, Yunho ^{[3
]}

Cho, Pyone ^{[4
]}

Jatlaoui, Tara C. ^{[4
]}

Kabbani, Sarah ^{[2
]}

Glidden, Emily ^{[5
]}

Ussery, Emily N. ^{[4
]}

Trivers, Katrina F. ^{[4
]}

Evans, Mary E. ^{[6
]}

King, Brian A. ^{[4
]}

Rose, Dale A. ^{[2
]}

Jones, Christopher M. ^{[6
]}

Baldwin, Grant ^{[6
]}

Delaney, Lisa J. ^{[7
]}

Briss, Peter ^{[4
]}

Ritchey, Matthew D. ^{[4
]}

Anderson, Kayla ^{[1
]}

Annor, Francis B. ^{[6
]}

Brown, Sharyn E. ^{[4
]}

Coulliette-Salmond, Angela D. ^{[2
]}

Cowan, Kristen N. ^{[5
]}

Dunn, Angela ^{[8
]}

Fleishauer, Aaron ^{[9
]}

Freed, Jennifer ^{[16
]}

Garcia, Macarena C. ^{[10
]}

Hamilton, Janet ^{[17
]}

Hayes, Donald ^{[4
]}

Hughes, Michelle M. ^{[1
]}

Israel, Mia ^{[17
]}

Kimball, Anne ^{[11
]}

Kisselburgh, Hannah ^{[2
]}

Layden, Jennifer ^{[12
]}

Lekiachvili, Akaki ^{[4
]}

Lozier, Matthew ^{[2
]}

Lynfield, Ruth ^{[13
]}

Meiman, Jonathan ^{[14
]}

Moritz, Erin D. ^{[5
]}

Njai, Rashid ^{[4
]}

Ratto, Jeffrey ^{[10
]}

Shafer, Sarah L. ^{[3
]}

Soroka, Stephen ^{[2
]}

Sterrett, Natalie ^{[3
,10
]}

Thomas, Kimberly R. ^{[10
]}

Wallace, Bailey ^{[1
]}

Werner, Angela K. ^{[5
]}

Wilken, Jason ^{[18
]}

Zapata, Lauren B. ^{[4
]}

Adkins, Susan Hocevar ^{[15
]}

Kiernan, Emily A. ^{[16
]}

机构：

[1] CDC, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USA

[2] CDC, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA

[3] CDC, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA

[4] CDC, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USA

[5] CDC, Natl Ctr Environm Hlth, Atlanta, GA 30333 USA

[6] CDC, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USA

[7] CDC, NIOSH, Atlanta, GA 30333 USA

[8] Utah Dept Hlth, Salt Lake City, UT 84116 USA

[9] North Carolina Dept Hlth & Human Serv, Raleigh, NC USA

[10] CDC, Ctr Surveillance Epidemiol & Lab Serv, Atlanta, GA 30333 USA

[11] CDC, Epidem Intelligence Serv, Natl Ctr HIVAIDS Viral Hepatitis STD & TB Prevent, Atlanta, GA 30333 USA

[12] Illinois Dept Publ Hlth, Springfield, IL 62761 USA

[13] Minnesota Dept Hlth, Minneapolis, MN 55414 USA

[14] Wisconsin Dept Hlth, Madison, WI USA

[15] CDC, Natl Ctr HIVAIDS Viral Hepatitis STD & TB Prevent, Atlanta, GA 30333 USA

[16] Agcy Tox Subst & Dis Registry, Atlanta, GA USA

[17] Council State & Terr Epidemiologists, Atlanta, GA USA

[18] Calif Dept Publ Hlth, Sacramento, CA USA

[19] CDC, Ctr Global Hlth, Atlanta, GA USA

来源：

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT | 2019年 / 68卷 / 46期

关键词：

D O I：

10.15585/mmwr.mm6846e1

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

CDC, the Food and Drug Administration (FDA), state and local health departments, and public health and clinical stakeholders are investigating a nationwide outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI) (1). As of November 13, 2019, 49 states, the District of Columbia, and two U.S. territories (Puerto Rico and U.S. Virgin Islands) have reported 2,172 EVALI cases to CDC, including 42 (1.9%) EVALI-associated deaths. To inform EVALI surveillance, including during the 2019-20 influenza season, case report information supplied by states for hospitalized and nonhospitalized patients with EVALI were analyzed using data collected as of November 5, 2019. Among 2,016 EVALI patients with available data on hospitalization status, 1,906 (95%) were hospitalized, and 110 (5%) were not hospitalized. Demographic characteristics of hospitalized and nonhospitalized patients were similar; most were male (68% of hospitalized versus 65% of nonhospitalized patients), and most were aged <35 years (78% of hospitalized versus 74% of nonhospitalized patients). These patients also reported similar use of tetrahydrocannabinol (THC)-containing products (83% of hospitalized versus 84% of nonhospitalized patients). Given the similarity between hospitalized and nonhospitalized EVALI patients, the potential for large numbers of respiratory infections during the emerging 2019-20 influenza season, and the potential difficulty in distinguishing EVALI from respiratory infections, CDC will no longer collect national data on nonhospitalized EVALI patients. Further collection of data on nonhospitalized patients will be at the discretion of individual state, local, and territorial health departments. Candidates for outpatient management of EVALI should have normal oxygen saturation (≥95% while breathing room air), no respiratory distress, no comorbidities that might compromise pulmonary reserve, reliable access to care, strong social support systems, and should be able to ensure follow-up within 24-48 hours of initial evaluation and to seek medical care promptly if respiratory symptoms worsen. Health care providers should emphasize the importance of annual influenza vaccination for all persons aged ≥6 months, including persons who use e-cigarette, or vaping, products (2,3).

引用

页码：1076 / 1080

页数：5

共 4 条

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