Single-Fraction Stereotactic Ablative Body Radiotherapy to the Lung- The Knockout Punch

被引:14
作者
Tjong, M. C. [1 ]
Louie, A., V [1 ]
Singh, A. K. [2 ]
Videtic, G. [3 ]
Stephans, K. [3 ]
Plumridge, N. [4 ]
Harden, S. [4 ]
Slotman, B. J. [5 ]
Alongi, F. [6 ,7 ]
Guckenberger, M. [8 ]
Siva, S. [4 ]
机构
[1] Sunnybrook Odette Canc Ctr, Toronto, ON, Canada
[2] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA
[3] Cleveland Clin, Cleveland, OH 44106 USA
[4] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[5] Amsterdam Univ Med Ctr VUMC, Amsterdam, Netherlands
[6] IRCCS Sacro Cuore Don Calabria Hosp, Adv Radiat Oncol Dept, Negrar Verona, Italy
[7] Univ Brescia, Brescia, Italy
[8] Univ Zurich, Univ Hosp Zurich, Zurich, Switzerland
关键词
Ablative; lung; metastasis; NSCLC; radiotherapy; stereotactic; MEDICALLY INOPERABLE PATIENTS; RADIATION-THERAPY; CANCER; OLIGOMETASTASES; OUTCOMES; PHASE-2; TUMORS; SBRT; METASTASES; MANAGEMENT;
D O I
10.1016/j.clon.2022.02.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This overview summarises the current evidence on efficacy and safety of single-fraction stereotactic ablative body radiotherapy (SABR) for primary lung cancers and lung metastases, in comparison with the more widely adapted multi-fraction SABR regimens. A literature search using the Medline database through PubMed was carried out using the following key words: ('stereotactic' or 'sabr' or 'sbrt'), ('radiotherapy' or 'radiation therapy'), ('lung' or 'thorax' or 'thoracic' or 'chest'), ('cancer' or 'metasta-' or 'oligometasta-'), alongside: (i) ('single-fraction' or 'single-dose') to identify trials and cohort studies with single-fraction SABR to lung malignant tumours and (ii) ('fraction' or 'schedule') limiting the search to 'clinical trial' and 'randomized controlled trial' to ensure thorough capture of lung SABR trials comparing different fractionations. The review discusses the radiobiological, technical and organ at risk considerations of single-fraction SABR to the lung. (C) 2022 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:E183 / E194
页数:12
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