A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland

被引：261

作者：

Perreten, V ^{[1
]}

Boerlin, P ^{[1
]}

机构：

[1] Univ Bern, Inst Vet Bacteriol, CH-3012 Bern, Switzerland

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 03期

关键词：

D O I：

10.1128/AAC.47.3.1169-1172.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new gene, sul3, which specifies a 263-amino-acid protein similar to a dihydropteroate synthase encoded by the 54-kb conjugative plasmid pVP440 from Escherichia coli was characterized. Expression of the cloned sul3 gene conferred resistance to sulfamethoxazole on E. coli. Two copies of the insertion element IS15Delta/26 flanked the region containing sul3. The sul3 gene was detected in one-third of the sulfonamide-resistant pathogenic E. coli isolates from pigs in Switzerland.

引用

页码：1169 / 1172

页数：4

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