A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland

被引：261

作者：

Perreten, V ^{[1
]}

Boerlin, P ^{[1
]}

机构：

[1] Univ Bern, Inst Vet Bacteriol, CH-3012 Bern, Switzerland

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 03期

关键词：

D O I：

10.1128/AAC.47.3.1169-1172.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new gene, sul3, which specifies a 263-amino-acid protein similar to a dihydropteroate synthase encoded by the 54-kb conjugative plasmid pVP440 from Escherichia coli was characterized. Expression of the cloned sul3 gene conferred resistance to sulfamethoxazole on E. coli. Two copies of the insertion element IS15Delta/26 flanked the region containing sul3. The sul3 gene was detected in one-third of the sulfonamide-resistant pathogenic E. coli isolates from pigs in Switzerland.

引用

页码：1169 / 1172

页数：4

共 24 条

[1] MINI-TN5 TRANSPOSON DERIVATIVES FOR INSERTION MUTAGENESIS, PROMOTER PROBING, AND CHROMOSOMAL INSERTION OF CLONED DNA IN GRAM-NEGATIVE EUBACTERIA [J].

DELORENZO, V ;

HERRERO, M ;

JAKUBZIK, U ;

TIMMIS, KN .

JOURNAL OF BACTERIOLOGY, 1990, 172 (11) :6568-6572

[2] PHYSICAL AND GENETIC-ANALYSIS OF THE COLD PLASMID [J].

FREY, J ;

GHERSA, P ;

PALACIOS, PG ;

BELET, M .

JOURNAL OF BACTERIOLOGY, 1986, 166 (01) :15-19

[3] Efflux of chloramphenicol by the Cm1A1 protein [J].

George, AM ;

Hall, RM .

FEMS MICROBIOLOGY LETTERS, 2002, 209 (02) :209-213

[4] A TIME-EFFICIENT, LINEAR-SPACE LOCAL SIMILARITY ALGORITHM [J].

HUANG, XQ ;

MILLER, W .

ADVANCES IN APPLIED MATHEMATICS, 1991, 12 (03) :337-357

[5] TRIMETHOPRIM AND SULFONAMIDE RESISTANCE [J].

HUOVINEN, P ;

SUNDSTROM, L ;

SWEDBERG, G ;

SKOLD, O .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (02) :279-289

[6]

Huovinen P, 2001, CLIN INFECT DIS, V32, P1608, DOI 10.1086/320532

[7] FUNCTIONAL-CHARACTERIZATION OF THE PROKARYOTIC MOBILE GENETIC ELEMENT IS26 [J].

IIDA, S ;

MOLLET, B ;

MEYER, J ;

ARBER, W .

MOLECULAR AND GENERAL GENETICS, 1984, 198 (01) :84-89

[8] Antimicrobial resistance and resistance gene determinants in clinical Escherichia coli from different animal species in Switzerland [J].

Lanz, R ;

Kuhnert, P ;

Boerlin, P .

VETERINARY MICROBIOLOGY, 2003, 91 (01) :73-84

[9] TRANSPOSITION OF AN ANTIBIOTIC-RESISTANCE ELEMENT IN MYCOBACTERIA [J].

MARTIN, C ;

TIMM, J ;

RAUZIER, J ;

GOMEZLUS, R ;

DAVIES, J ;

GICQUEL, B .

NATURE, 1990, 345 (6277) :739-743

[10] Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes [J].

Naas, T ;

Mikami, Y ;

Imai, T ;

Poirel, L ;

Nordmann, P .

JOURNAL OF BACTERIOLOGY, 2001, 183 (01) :235-249

← 1 2 3 →