Synthesis and radical cyclization of 2-allylamino-3-chloropropylphenyl sulfones to 2,4-disubstituted pyrrolidines

被引：0

作者：

Giovannini, R ^{[1
]}

Petrini, M ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

SYNLETT | 1998年 / 01期

关键词：

vinyl sulfones; allylic amines; conjugate addition; radical cyclization; pyrrolidines;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allylic and propargylic amines give a chemoselective conjugate addition to 3-chlorovinyl surfones under appropriate conditions. The resulting allylamino sulfones are cyclized using tributyltin hydride to afford 2,4-disubstitued pyrrolidines in satisfactory yield.

引用

页码：90 / +

页数：4

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