Microvascular ischemia in patients with myotonic dystrophy

被引：10
|
作者：
Itoh, H
Shimizu, M
Horita, Y
Ino, H
Taguchi, T
Kajinami, K
Yagi, K
Chujo, D
Mabuchi, H
机构：
[1] Kanazawa Univ, Sch Med, Dept Internal Med 2, Kanazawa, Ishikawa 9208640, Japan
[2] Keiju Gen Hosp, Dept Cardiol, Nanao, Ishikawa, Japan
来源：
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 2000年 / 64卷 / 09期
关键词：
dipyridamole; microvascular ischemia; myotonic dystrophy; thallium-301 myocardial scintigraphy;
D O I：
10.1253/jcj.64.720
中图分类号：
N09 [自然科学史]; B [哲学、宗教];
学科分类号：
01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;
摘要：
Two women with myotonic dystrophy underwent dipyridamole thallium-201 (Tl-201) myocardial perfusion imaging, after which one patient developed flat T waves in lead I and aVL, and inverted T waves in leads V2-6. The other patient developed a nonspecific intraventricular block that progressed to complete left bundle branch block and was associated with chest discomfort. Reversible scintigraphic defects were observed in both women. Although there was evidence that suggested myocardial ischemia on the ECG changes and Tl-201 scintigraphic findings, coronary angiography demonstrated no significant stenoses in either patient. These findings suggest that microvascular dysfunction may lead to myocardial ischemia and conduction disturbances in patients with myotonic dystrophy.
引用
收藏
页码：720 / 722
页数：3
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