Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study

被引：32

作者：

Guo, Jianfeng ^{[1
]}

Yang, Lu ^{[1
]}

Cai, Jing ^{[1
]}

Xu, Linjuan ^{[1
]}

Min, Jie ^{[1
]}

Shen, Yi ^{[1
]}

Xiong, Zhoufang ^{[1
]}

Dong, Weihong ^{[1
]}

Bunyamanop, Vichitra ^{[1
]}

Wang, Zehua ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Obstet & Gynecol, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R China

来源：

ONCOTARGETS AND THERAPY | 2018年 / 11卷

基金：

中国国家自然科学基金;

关键词：

early cervical cancer; clinical outcomes; laparoscopic radical hysterectomy; pelvic lymphadenectomy; retrospective study; NODE DISSECTION; EXPERIENCE; CARCINOMA;

D O I：

10.2147/OTT.S156064

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Objective: To compare clinical outcomes in laparoscopic and open radical hysterectomy with pelvic lymphadenectomy (LRH) in early cervical cancer without the selection bias. Methods: One special retrospective study was conducted with more than 400 patients involved in laparoscopic procedure. Results: Our results suggest that estimated blood loss and transfusion requirements were significantly lower in the LRH group. Postoperative hospital stay was also significantly shorter in the LRH group. Significant difference was found in the number of pelvic lymph nodes retrieved between the LRH and open radical hysterectomy with pelvic lymphadenectomy (ORH) groups. There were no differences in operating time, perioperative complications, progression-free survival, and overall survival between the LRH and ORH groups. Conclusion: LRH can be considered a safe and effective alternative to conventional open surgery (ORH) for early-stage cervical cancer.

引用

页码：5903 / 5908

页数：6

共 27 条

[1] RADICAL HYSTERECTOMY FOR INVASIVE CERVICAL-CANCER - A 25-YEAR PROSPECTIVE EXPERIENCE WITH THE MIAMI TECHNIQUE [J].

AVERETTE, HE ;

NGUYEN, HN ;

DONATO, DM ;

PENALVER, MA ;

SEVIN, BU ;

ESTAPE, R ;

LITTLE, WA .

CANCER, 1993, 71 (04) :1422-1437

[2]

AYHAN A, 1991, EUR J SURG ONCOL, V17, P492

[3] Postoperative pain and perioperative outcomes after laparoscopic radical hysterectomy and abdominal radical hysterectomy in patients with early cervical cancer: a randomised controlled trial [J].

Campos, Luciana Silveira ;

Limberger, Leo Francisco ;

Stein, Airton Tetelbom ;

Kalil, Antonio Nocchi .

TRIALS, 2013, 14

[4] Laparoscopic radical hysterectomy for cervical cancer [J].

Canis, M ;

Mage, G ;

Pouly, JL ;

Pomel, C ;

Wattiez, A ;

Glowaczover, E ;

Bruhat, MA .

BAILLIERES CLINICAL OBSTETRICS AND GYNAECOLOGY, 1995, 9 (04) :675-689

[5]

Comerci G, 1998, INT J GYNECOL CANCER, V8, P23

[6] Technology for minimal access surgery [J].

Cuschieri, A .

BRITISH MEDICAL JOURNAL, 1999, 319 (7220) :1304-U73

[7] Comparison of total laparoscopic and abdominal radical hysterectomy for patients with early-stage cervical cancer [J].

Frumovitz, Michael ;

dos Reis, Ricardo ;

Sun, Charlotte C. ;

Milam, Michael R. ;

Bevers, Michael W. ;

Brown, Jubilee ;

Slomovitz, Brian M. ;

Ramirez, Pedro T. .

OBSTETRICS AND GYNECOLOGY, 2007, 110 (01) :96-102

[8]

Hsieh YY, 1998, J REPROD MED, V43, P528

[9] Learning curve analysis of laparoscopic radical hysterectomy and lymph node dissection in early cervical cancer [J].

Hwang, Jong Ha ;

Yoo, Heon Jong ;

Joo, Jungnam ;

Kim, Sohee ;

Lim, Myong Cheol ;

Song, Yong Jung ;

Park, Sang-Yoon .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2012, 163 (02) :219-223

[10]

Kim DH, 1998, J AM ASSOC GYN LAP, V5, P411

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