High-definition transcranial direct current simulation (HD-tDCS) for persistent auditory hallucinations in schizophrenia

被引:33
作者
Sreeraj, Vanteemar S. [1 ]
Dinakaran, Damodharan [1 ]
Parlikar, Rujuta [1 ]
Chhabra, Harleen [1 ]
Selvaraj, Sowmya [1 ]
Shivakumar, Venkataram [1 ]
Bose, Anushree [1 ]
Narayanaswamy, Janardhanan C. [1 ]
Venkatasubramanian, Ganesan [1 ]
机构
[1] Natl Inst Mental Hlth & Neurosci, Dept Psychiat, WISER Neuromodulat Program, Bangalore, Karnataka, India
基金
英国惠康基金;
关键词
Schizophrenia; Auditory hallucinations; HD-tDCS; DIRECT-CURRENT STIMULATION; PSYCHIATRIC-DISORDERS; INSIGHT; VARIABILITY; SCALE;
D O I
10.1016/j.ajp.2018.08.008
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Conventional transcranial Direct Current Stimulation (tDCS) has been reported to alleviate persistent auditory hallucinations (AH) in schizophrenia as an add-on intervention. High-Definition tDCS (HD-tDCS), an optimized form of tDCS, has the potential for more focalized neuromodulation. In this study, add-on HD-tDCS (5 days twice daily session with 2-mA cathodal current on left temporo-parietal junction) using 4 x 1 ring montage significantly reduced persistent AH (t = 3.6; p < 0.01) in schizophrenia patients (N = 19). Add-on HD-tDCS has promising potential to treat persisting AH in schizophrenia. This needs further systematic research.
引用
收藏
页码:46 / 50
页数:5
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