Impact of chocolate on the cardiovascular health

被引:25
|
作者
Gammone, Maria Alessandra [1 ]
Efthymakis, Konstantinos [2 ,3 ]
Pluchinotta, Francesca Romana [4 ]
Bergante, Sonia [4 ]
Tettamanti, Guido [4 ]
Riccioni, Graziano [5 ]
D'Orazio, Nicolantonio [1 ]
机构
[1] Univ G dAnnunzio, Dept Med Oral & Biotechnol Sci, Human & Clin Nutr Unit, Via Vestini 31, I-66013 Chieti, Italy
[2] G DAnnunzio Univ & Fdn, Dept Med & Ageing Sci, Via Luigi Polacchi 11, I-66013 Chieti, Italy
[3] G DAnnunzio Univ & Fdn, Ctr Excellence Ageing & Translat Med CeSI MeT, Via Luigi Polacchi 11, I-66013 Chieti, Italy
[4] IRCCS S Donato Hosp, Piazza Edmondo Malan, I-20097 Milan, Italy
[5] San Camillo De Lellis Hosp, Cardiol Unit, Via Isonzo 1, I-71043 Manfredonia, Fg, Italy
来源
FRONTIERS IN BIOSCIENCE-LANDMARK | 2018年 / 23卷
关键词
Nutrition; Cocoa; Chocolate; Hearth; Arrhythmias; Cardiovascular Risk; Review; BLOOD-PRESSURE; DARK CHOCOLATE; ATRIAL-FIBRILLATION; DEPENDENT VASODILATION; ENDOTHELIAL FUNCTION; INSULIN SENSITIVITY; MARINE BIOACTIVES; COCOA CONSUMPTION; THEOBROMA-CACAO; NITRIC-OXIDE;
D O I
10.2741/4620
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The antioxidants such as polyphenols, especially flavonols, present in large quantitites in cocoa, cause vasodilation, modulate inflammatory markers and cardiovascular health, and possess a range of protective cardiovascular effects. On the other hand, overconsumption of chocolate can lead to tachyarrhythmias, supraventricular tachycardia, atrial fibrillation, ventricular tachycardia and ventricular fibrillation due to its caffeine content. This review describes both the cardioprotective and adverse effects of chocolate and its constituents.
引用
收藏
页码:852 / 864
页数:13
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