A Learning-Based Model to Evaluate Hospitalization Priority in COVID-19 Pandemics

被引:19
作者
Zheng, Yichao [1 ,4 ]
Zhu, Yinheng [1 ,4 ]
Ji, Mengqi [3 ,4 ]
Wang, Rongpin [2 ]
Liu, Xinfeng [2 ]
Zhang, Mudan [2 ]
Liu, Jun [5 ,6 ]
Zhang, Xiaochun [7 ]
Qin, Choo Hui [1 ,4 ]
Fang, Lu [1 ,4 ]
Ma, Shaohua [1 ,4 ]
机构
[1] Tsinghua Univ, Tsinghua Berkeley Shenzhen Inst TBSI, Shenzhen 518055, Peoples R China
[2] Guizhou Prov Peoples Hosp, Dept Radiol, Guiyang 550002, Peoples R China
[3] Tsinghua Univ, Dept Automat, Beijing 100084, Peoples R China
[4] Tsinghua Univ, Shenzhen Int Grad Sch SIGS, Shenzhen 518055, Peoples R China
[5] Cent South Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Peoples R China
[6] Qual Control Ctr, Dept Radiol, Changsha 410011, Peoples R China
[7] Wuhan Univ, Zhongnan Hosp, Dept Radiol, Wuhan 43000, Peoples R China
来源
PATTERNS | 2020年 / 1卷 / 06期
基金
中国国家自然科学基金;
关键词
COVID-19; DSML 2: Proof-of-Concept: Data science output has been formulated; implemented; and tested for one domain/problem; hospitalization priority; learning-based model;
D O I
10.1016/j.patter.2020.100092
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The emergence of the novel coronavirus disease 2019 (COVID-19) is placing an increasing burden on healthcare systems. Although the majority of infected patients experience non-severe symptoms and can be managed at home, some individuals develop severe symptoms and require hospital admission. Therefore, it is critical to efficiently assess the severity of COVID-19 and identify hospitalization priority with precision. In this respect, a four-variable assessment model, including lymphocyte, lactate dehydrogenase, C-reactive protein, and neutrophil, is established and validated using the XGBoost algorithm. This model is found to be effective in identifying severe COVID-19 cases on admission, with a sensitivity of 84.6%, a specificity of 84.6%, and an accuracy of 100% to predict the disease progression toward rapid deterioration. It also suggests that a computation-derived formula of clinical measures is practically applicable for healthcare administrators to distribute hospitalization resources to the most needed in epidemics and pandemics.
引用
收藏
页数:9
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