Human Metapneumovirus

被引：25
作者：
Hermos, Christina R. [2 ]
Vargas, Sara O. [3 ,4 ]
McAdam, Alexander J. [1 ,3 ]
机构：
[1] Childrens Hosp Boston, Dept Lab Med, Infect Dis Diagnost Div, Boston, MA 02115 USA
[2] Childrens Hosp Boston, Dept Med, Div Infect Dis, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[4] Childrens Hosp Boston, Dept Pathol, Boston, MA 02115 USA
来源：
CLINICS IN LABORATORY MEDICINE | 2010年 / 30卷 / 01期
关键词：
Metapneumovirus; Respiratory syncytial virus; Respiratory infection; Bronchiolitis; RESPIRATORY SYNCYTIAL VIRUS; OBSTRUCTIVE PULMONARY-DISEASE; COMMUNITY-ACQUIRED PNEUMONIA; LINKED-IMMUNOSORBENT-ASSAY; DIFFERENT CELL-LINES; TRACT INFECTIONS; YOUNG-CHILDREN; GENETIC-VARIABILITY; G-GLYCOPROTEIN; BALB/C MICE;
D O I：
10.1016/j.cll.2009.10.002
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Respiratory tract infections (RTI) are the leading cause of death in low-income countries and the second leading cause of death worldwide in children less than 5 years old. Most RTI are viral. Human metapneumovirus (hMPV) was discovered in 2001 in routine viral cultures of respiratory specimens from children with RTI and has been implicated as a common cause of RTI in children and adults and a cause of severe disease in immunocompromised hosts. This article describes the microbiology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment, prognosis, long-term outcome, immunity and reinfection of hMPV.
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页码：131 / +
页数：19
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