The Advances of Carbon Nanotubes in Cancer Diagnostics and Therapeutics

被引:61
作者
Chen, Zhou [1 ,2 ]
Zhang, Aili [3 ]
Wang, Xiaobing [4 ,5 ]
Zhu, Jing [6 ]
Fan, Yamin [7 ]
Yu, Hongmei [8 ]
Yang, Zhaogang [7 ]
机构
[1] Nanjing Tech Univ, Sch Mech & Power Engn, Nanjing 211800, Jiangsu, Peoples R China
[2] Suzhou Yiheyongli New Energy Co Ltd, Suzhou 215400, Jiangsu, Peoples R China
[3] Cleveland Clin, Dept Canc Biol, Cleveland, OH 44195 USA
[4] Chinese Acad Med Sci, Canc Inst & Hosp, Tumor Marker Res Ctr, Beijing 100021, Peoples R China
[5] Peking Union Med Coll, Beijing 100021, Peoples R China
[6] Ohio State Univ, Coll Pharm, Columbus, OH 43210 USA
[7] Ohio State Univ, Dept Chem & Biomol Engn, Columbus, OH 43210 USA
[8] Jilin Univ, China Japan Union Hosp, Changchun 130021, Jilin, Peoples R China
关键词
IN-VIVO; DRUG-DELIVERY; PHOTOTHERMAL THERAPY; TARGETED DELIVERY; THERMAL ABLATION; PHOTOACOUSTIC TOMOGRAPHY; CELLULAR UPTAKE; QUANTUM DOTS; TUMOR-CELLS; NANOPARTICLES;
D O I
10.1155/2017/3418932
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Carbon nanotubes (CNTs), one of the unique one-dimensional nanomaterials, have gained great attention because of their specific characters, versatile functionalization chemistry, and biological compatibility in the past few decades. CNTs can be functionalized via different methods to perform their specific functions. CNTs have been used in various areas of biomedicine as nanocarriers, including cancer diagnosis and therapy. Different molecules such as peptide, antigen, and nucleic acid can be delivered to cancer cells by CNTs with high efficiency. In this review, we summarized the properties of CNTs and the method of CNTs functionalization and illustrated their application in cancer diagnosis and therapy.
引用
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页数:13
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