Verification of high dose rate 192Ir source position during brachytherapy treatment

被引：16

作者：

Batic, M. ^{[1
]}

Burger, J. ^{[2
]}

Cindro, V. ^{[1
]}

Kramberger, G. ^{[1
]}

Mandic, I. ^{[1
]}

Mikuz, M. ^{[1
,3
]}

Studen, A. ^{[1
]}

Zavrtanik, M. ^{[1
]}

机构：

[1] Jozef Stefan Inst, Expt Particle Phys Dept, Ljubljana, Slovenia

[2] Inst Oncol, Dept Radiophys, Ljubljana, Slovenia

[3] Univ Ljubljana, Dept Phys, Ljubljana 61000, Slovenia

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2010年 / 617卷 / 1-3期

关键词：

Source localization; Brachytherapy; Silicon pixel detectors; Verification; CAMERA;

D O I：

10.1016/j.nima.2009.09.122

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

A system for in vivo tracking of 1 Ci Ir-192 source during brachytherapy treatment has been built using high resistivity silicon pad detectors as image sensors and knife-edge lead pinholes as collimators. The sensors consist of 256 pads arranged in 32 x 8 grid with pad size 1.4 x 1.4 mm(2) and 1 mm thickness. The sensors have two metal layers, enabling connection of readout electronics (VATAGP3_1 chips) at the edge of the detector. With source self-images obtained from a dual-pinhole system, location of the source can be reconstructed in three dimensions in real time, allowing on-line detection of deviations from planned treatment. The system was tested with 1 Ci Ir-192 clinical source in air and plexi-glass phantom. The movements of the source could be tracked in a field of view of approximately 20 x 20 x 20 cm(3) with absolute precision of about 5 mm. Positions of the source, relative to the first measured source position, could be mapped with precision of around 3 mm. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：206 / 208

页数：3

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