Analysis of DOSY and GPC-NMR experiments on polymers by multivariate curve resolution

Multivariate curve resolution (MCR) was successfully applied to the analysis of DOSY experiments on polymer mixtures and GPC-NMR experiments on industrial copolymer samples. MCR generates pure factors of spectral and concentration profiles using, successively, principal factor analysis, Varimax rotation, and alternating least-squares optimization. The method described is robust and can be directly applied to DOSY and GPC-NMR data and one obtains H-1 NMR spectra of the individual compounds with their corresponding diffusion or elution profiles, respectively. (C) 1998 Academic Press.