Pheochromocytoma in a 49-year-old woman presenting with acute myocardial infarction: A case report

被引:1
作者
Wu, Hao-Yu [1 ]
Cao, Yi-Wei [2 ]
Gao, Tian-Jiao [3 ]
Fu, Jian-Li [4 ]
Liang, Lei [1 ]
机构
[1] Shaanxi Prov Peoples Hosp, Dept Cardiol, Xian 710068, Shaanxi, Peoples R China
[2] Shaanxi Prov Peoples Hosp, Dept Electrocardiol, 256 West Youyi Rd, Xian 710068, Shaanxi, Peoples R China
[3] Xian Childrens Hosp, Dept Gastroenterol, Xian 710068, Shaanxi, Peoples R China
[4] Shaanxi Prov Peoples Hosp, Ultrason Diag Ctr, Xian 710068, Shaanxi, Peoples R China
关键词
Pheochromocytoma; Catecholamine; Cardiac complications; Acute myocardial infarction; Chest pain; Case report; MANAGEMENT;
D O I
10.12998/wjcc.v9.i15.3752
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Pheochromocytoma is a rare endocrine tumor arising from chromaffin cells and having extensive and profound effects on the cardiovascular system by continuously or intermittently releasing catecholamines. The clinical manifestations of pheochromocytoma are diverse, and the typical triad, including episodic headache, palpitations, and sweating, only occurs in 24% of pheochromocytoma patients, which often misleads clinicians into making an incorrect diagnosis. We herein report the case of a patient with intermittent chest pain and elevated myocardial enzymes for 2 years who was diagnosed with pheochromocytoma. CASE SUMMARY A 49-year-old woman presented with intermittent chest pain for 2 years. Two years ago, the patient experienced chest pain and was diagnosed with acute myocardial infarction, with 25% stenosis in the left circumflex. The patient still had intermittent chest pain after discharge. Two hours before admission to our hospital, the patient experienced chest pain with nausea and vomiting, lasting for 20 min. Troponin I and urinary norepinephrine and catecholamine levels were elevated. An electrocardiogram indicated QT prolongation and ST-segment depression in leads II, III, aVF, and V3-V6. A coronary computed tomography angiogram revealed no evidence of coronary artery disease. Echocardiography showed left ventricular enlargement and a decreased posterior inferior wall motion amplitude. Contrast-enhanced computed tomography demonstrated an inhomogeneous right adrenal mass. The patient successfully underwent laparoscopic right adrenalectomy, and histopathology confirmed adrenal pheochromocytoma. During the first-year follow-up visits, the patient was asymptomatic. The abnormal changes on echocardiography and electrocardiogram disappeared. CONCLUSION Clinicians should be aware of pheochromocytoma. A timely and accurate diagnosis of pheochromocytoma is essential for alleviating serious cardiac complications.
引用
收藏
页码:3752 / 3757
页数:7
相关论文
共 20 条
[1]   Pheochromocytoma-Induced Takotsubo Cardiomyopathy [J].
Afana, Majed ;
Panchal, Rishi J. ;
Simon, Rebecca M. ;
Hejab, Amal ;
Lahiri, Sharon W. ;
Khandelwal, Akshay K. ;
Hudson, Michael P. .
TEXAS HEART INSTITUTE JOURNAL, 2019, 46 (02) :124-127
[2]  
Agrawal S, 2017, WORLD J CARDIOL, V9, P255, DOI 10.4330/wjc.v9.i3.255
[3]   Massive pheochromocytoma [J].
Anai, Terumitsu ;
Oka, Kosuke ;
Yokota, Yuya ;
Nishimura, Yoshito ;
Hagiya, Hideharu ;
Otsuka, Fumio .
CLINICAL CASE REPORTS, 2020, 8 (11) :2308-2309
[4]   Risk factors for postoperative cardiovascular morbidity after pheochromocytoma surgery: a large single center retrospective analysis [J].
Bai, Song ;
Yao, Zichuan ;
Zhu, Xianqing ;
Li, Zidong ;
Jiang, Yunzhong ;
Wang, Rongzhi ;
Wen, Ning .
ENDOCRINE JOURNAL, 2019, 66 (02) :165-173
[5]   Outcomes analysis in patients undergoing laparoscopic adrenalectomy for hormonally active adrenal tumors [J].
Brunt, LM ;
Moley, JF ;
Doherty, DM ;
Lairmore, TC ;
DeBenedetti, MK ;
Quasebarth, MA .
SURGERY, 2001, 130 (04) :629-634
[6]   Adverse drug reactions in patients with phaeochromocytoma - Incidence, prevention and management [J].
Eisenhofer, Graeme ;
Rivers, Graham ;
Rosas, Alejandro L. ;
Quezado, Zena ;
Manger, William M. ;
Pacak, Karel .
DRUG SAFETY, 2007, 30 (11) :1031-1062
[7]  
Farrugia Frederick-Anthony, 2019, Endocr Regul, V53, P191, DOI 10.2478/enr-2019-0020
[8]   Cardiovascular complications in patients with pheochromocytoma: A mini-review [J].
Galetta, Fabio ;
Franzoni, Ferdinando ;
Bernini, Giampaolo ;
Poupak, Fallawi ;
Carpi, Angelo ;
Cini, Giuseppe ;
Tocchini, Leonardo ;
Antonelli, Alessandro ;
Santoro, Gino .
BIOMEDICINE & PHARMACOTHERAPY, 2010, 64 (07) :505-509
[9]   Cardiovascular Manifestations of Pheochromocytoma [J].
Gu, Yu Wei ;
Poste, Jennifer ;
Kunal, Mehta ;
Schwarcz, Monica ;
Weiss, Irene .
CARDIOLOGY IN REVIEW, 2017, 25 (05) :215-222
[10]   Tako-Tsubo cardiomyopathy induced by pheochromocytoma [J].
Hernandez-Montoliu, Laura ;
Simo-Servat, Andreu ;
Villabona, Carles .
ENDOCRINOLOGIA DIABETES Y NUTRICION, 2018, 65 (09) :549-551