Quantitative measurements of proton spin-lattice (T1) and spin-spin (T2) relaxation times in the mouse brain at 7.0 T

被引：43

作者：

Guilfoyle, DN

Dyakin, VV

O'Shea, J

Pell, GS

Helpern, JA

机构：

[1] Nathan S Kline Inst Psychiat Res, Div Med Phys, Orangeburg, NY 10962 USA

[2] Nathan S Kline Inst Psychiat Res, Ctr Adv Brain Imaging, Orangeburg, NY 10962 USA

[3] NYU, Sch Med, Dept Radiol, New York, NY USA

[4] NYU, Sch Med, Dept Psychiat, New York, NY USA

[5] NYU, Sch Med, Dept Physiol & Neurosci, New York, NY USA

来源：

MAGNETIC RESONANCE IN MEDICINE | 2003年 / 49卷 / 03期

关键词：

T-1; T-2; k-space; snapshot FLASH; hippocampus; corpus callosum; retrosplenial granular (RSG) cortex;

D O I：

10.1002/mrm.10371

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The goal of this work is to provide regional T-1 and T-2 values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T-1 in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T-2 measurements were made in the same regions using a single spin echo sequence repeated at six separate echo times. Both T-1 and T-2 measurements were validated with phantom measurements. (C) 2003 Wiley-Liss, Inc.

引用

页码：576 / 580

页数：5

共 21 条

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