Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

被引：38

作者：

Gayet-Ageron, Angele ^{[1
,2
]}

Sednaoui, Patrice ^{[4
]}

Lautenschlager, Stephan ^{[5
]}

Ferry, Tristan ^{[6
]}

Toutous-Trellu, Laurence ^{[3
]}

Cavassini, Matthias ^{[7
]}

Yassir, Fatima ^{[6
]}

de Tejada, Begona Martinez ^{[3
]}

Emonet, Stephane ^{[3
]}

Combescure, Christophe ^{[3
]}

Schrenzel, Jacques ^{[3
]}

Perneger, Thomas ^{[3
]}

机构：

[1] Univ Hosp Geneva, Div Clin Epidemiol, CH-1211 Geneva 14, Switzerland

[2] Univ Hosp Geneva, Infect Control Program, CH-1211 Geneva 14, Switzerland

[3] Univ Hosp Geneva, CH-1211 Geneva 14, Switzerland

[4] Inst Alfred Fournier, Paris, France

[5] Triemli Municipal Hosp, Zurich, Switzerland

[6] Hosp Civils Lyon, Lyon, France

[7] CHU Vaudois, CH-1011 Lausanne, Switzerland

来源：

EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 01期

关键词：

REAL-TIME PCR;

D O I：

10.3201/eid2101.140790

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.

引用

页码：127 / 129

页数：3

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