Epstein-Barr virus: LMP1 masquerades as an active receptor

被引：63

作者：

Eliopoulos, AG ^{[1
]}

Rickinson, AB ^{[1
]}

机构：

[1] Univ Birmingham, CRC, Inst Canc Studies, Birmingham B15 2TA, W Midlands, England

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 06期

关键词：

D O I：

10.1016/S0960-9822(98)70123-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Epstein-Barr virus protein LMP1 is essential for transformation of resting B cells by the virus, but how it works is unclear. Recent results suggest that LMP1 acts as a constitutively active receptor that shares certain characteristics with members of the tumour necrosis factor receptor superfamily. (C) Current Biology Ltd ISSN 0960-9822.

引用

页码：R196 / R198

页数：3

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