Epstein-Barr virus: LMP1 masquerades as an active receptor

被引:63
作者
Eliopoulos, AG [1 ]
Rickinson, AB [1 ]
机构
[1] Univ Birmingham, CRC, Inst Canc Studies, Birmingham B15 2TA, W Midlands, England
关键词
D O I
10.1016/S0960-9822(98)70123-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Epstein-Barr virus protein LMP1 is essential for transformation of resting B cells by the virus, but how it works is unclear. Recent results suggest that LMP1 acts as a constitutively active receptor that shares certain characteristics with members of the tumour necrosis factor receptor superfamily. (C) Current Biology Ltd ISSN 0960-9822.
引用
收藏
页码:R196 / R198
页数:3
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