Science and society - Drug addiction: the neurobiology of behaviour gone awry

被引：386
作者：
Volkow, ND [1 ]
Li, TK
机构：
[1] NIDA, Bethesda, MD 20892 USA
[2] NIAAA, Bethesda, MD 20892 USA
来源：
NATURE REVIEWS NEUROSCIENCE | 2004年 / 5卷 / 12期
关键词：
D O I：
10.1038/nrn1539
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Drug addiction manifests as a compulsive drive to take a drug despite serious adverse consequences. This aberrant behaviour has traditionally been viewed as bad 'choices' that are made voluntarily by the addict. However, recent studies have shown that repeated drug use leads to long-lasting changes in the brain that undermine voluntary control. This, combined with new knowledge of how environmental, genetic and developmental factors contribute to addiction, should bring about changes in our approach to the prevention and treatment of addiction.
引用
收藏
页码：963 / 970
页数：8
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