Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment

被引：22

作者：

Liu, Lidong ^{[1
]}

Cui, Yutong ^{[1
]}

Zhou, Qiongjie ^{[1
,3
]}

Zhao, Huanqiang ^{[1
]}

Li, Xiaotian ^{[1
,2
,3
]}

机构：

[1] Fudan Univ, Obstet & Gynecol Hosp, Fangxie Rd 419, Shanghai 200011, Peoples R China

[2] Fudan Univ, Inst Biomed Sci, Shanghai, Peoples R China

[3] Shanghai Key Lab Female Reprod Endocrine Related, Shanghai, Peoples R China

来源：

ORPHANET JOURNAL OF RARE DISEASES | 2021年 / 16卷 / 01期

基金：

美国国家科学基金会;

关键词：

Diagnosis; Hemophagocytic lymphohistiocytosis; Infection; Pregnancy; Treatment; CELL LYMPHOMA; TRANSPLACENTAL TRANSMISSION; LUPUS-ERYTHEMATOSUS; MANAGEMENT; INFECTION; ETOPOSIDE; EBV; PREECLAMPSIA; PLACENTA; HLH;

D O I：

10.1186/s13023-021-01790-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Hemophagocytic lymphohistiocytosis during pregnancy is rare; it is often misdiagnosed, resulting in a high maternal and foetal mortality rate. Herein, based on limited case reports including antepartum and postpartum cases, we reviewed the current studies of pregnancy-related hemophagocytic lymphohistiocytosis, and compared the epidemiology, aetiology, diagnosis and treatment of pregnancy-related hemophagocytic lymphohistiocytosis with non-pregnancy, enriching the understanding of hemophagocytic lymphohistiocytosis and its treatment in obstetrics.

引用

页数：10

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