Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment

被引：26
作者：
Liu, Lidong [1 ]
Cui, Yutong [1 ]
Zhou, Qiongjie [1 ,3 ]
Zhao, Huanqiang [1 ]
Li, Xiaotian [1 ,2 ,3 ]
机构：
[1] Fudan Univ, Obstet & Gynecol Hosp, Fangxie Rd 419, Shanghai 200011, Peoples R China
[2] Fudan Univ, Inst Biomed Sci, Shanghai, Peoples R China
[3] Shanghai Key Lab Female Reprod Endocrine Related, Shanghai, Peoples R China
来源：
ORPHANET JOURNAL OF RARE DISEASES | 2021年 / 16卷 / 01期
基金：
美国国家科学基金会;
关键词：
Diagnosis; Hemophagocytic lymphohistiocytosis; Infection; Pregnancy; Treatment; CELL LYMPHOMA; TRANSPLACENTAL TRANSMISSION; LUPUS-ERYTHEMATOSUS; MANAGEMENT; INFECTION; ETOPOSIDE; EBV; PREECLAMPSIA; PLACENTA; HLH;
D O I：
10.1186/s13023-021-01790-9
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Hemophagocytic lymphohistiocytosis during pregnancy is rare; it is often misdiagnosed, resulting in a high maternal and foetal mortality rate. Herein, based on limited case reports including antepartum and postpartum cases, we reviewed the current studies of pregnancy-related hemophagocytic lymphohistiocytosis, and compared the epidemiology, aetiology, diagnosis and treatment of pregnancy-related hemophagocytic lymphohistiocytosis with non-pregnancy, enriching the understanding of hemophagocytic lymphohistiocytosis and its treatment in obstetrics.
引用
收藏
页数：10
相关论文
共 50 条
[1]   Pregnancy induced haemophagocytic syndrome [J].
Shukla A. ;
Kaur A. ;
Hira H.S. .
The Journal of Obstetrics and Gynecology of India, 2013, 63 (3) :203-205
[2]  
Arewa O P, 2011, West Afr J Med, V30, P66
[3]   Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study [J].
Bergsten, Elisabet ;
Horne, AnnaCarin ;
Arico, Maurizio ;
Astigarraga, Itziar ;
Egeler, R. Maarten ;
Filipovich, Alexandra H. ;
Ishii, Eiichi ;
Janka, Gritta ;
Ladisch, Stephan ;
Lehmberg, Kai ;
McClain, Kenneth L. ;
Minkov, Milen ;
Montgomery, Scott ;
Nanduri, Vasanta ;
Rosso, Diego ;
Henter, Jan-Inge .
BLOOD, 2017, 130 (25) :2728-2738
[4]   Critical care management of patients with hemophagocytic lymphohistiocytosis [J].
Buyse, Sophie ;
Teixeira, Luis ;
Galicier, Lionel ;
Mariotte, Eric ;
Lemiale, Virginie ;
Seguin, Amelie ;
Bertheau, Philippe ;
Canet, Emmanuel ;
de Labarthe, Adrienne ;
Darmon, Michael ;
Rybojad, Michel ;
Schlemmer, Benoit ;
Azoulay, Elie .
INTENSIVE CARE MEDICINE, 2010, 36 (10) :1695-1702
[5]   Transplacental transmission of natural-killer-cell lymphoma [J].
Catlin, EA ;
Roberts, JD ;
Erana, R ;
Preffer, FI ;
Ferry, JA ;
Kelliher, AS ;
Atkins, L ;
Weinstein, HJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (02) :85-91
[6]   Hemophagocytic syndrome in pregnancy [J].
Chmait, RH ;
Meimin, DL ;
Koo, CH ;
Huffaker, J .
OBSTETRICS AND GYNECOLOGY, 2000, 95 (06) :1022-1024
[7]   Hemophagocytic lymphohistiocytosis in pregnancy: a case report and review of treatment options [J].
Dunn, Tamara ;
Cho, May ;
Medeiros, Bruno ;
Logan, Aaron ;
Ungewickell, Alexander ;
Liedtke, Michaela .
HEMATOLOGY, 2012, 17 (06) :325-328
[8]   Development and Validation of the HScore, a Score for the Diagnosis of Reactive Hemophagocytic Syndrome [J].
Fardet, Laurence ;
Galicier, Lionel ;
Lambotte, Olivier ;
Marzac, Christophe ;
Aumont, Cedric ;
Chahwan, Doumit ;
Coppo, Paul ;
Hejblum, Gilles .
ARTHRITIS & RHEUMATOLOGY, 2014, 66 (09) :2613-2620
[9]   Disseminated herpes simplex virus manifesting as pyrexia and cervicitis and leading to reactive hemophagocytic syndrome in pregnancy [J].
Goulding, Elizabeth A. ;
Barnden, Kristine R. .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2014, 180 :198-199
[10]   B-cell lymphoma during pregnancy associated with hemophagocytic syndrome and placental involvement [J].
Hanaoka, Mio ;
Tsukimori, Kiyomi ;
Hojo, Satoshi ;
Abe, Yasunobu ;
Mutou, Toshitaka ;
Muta, Koichiro ;
Iwasa, Atsuko ;
Yao, Takashi ;
Nakano, Hitoo .
CLINICAL LYMPHOMA & MYELOMA, 2007, 7 (07) :486-490
12345