LAB-GROWN STRUCTURES MIMIC HUMAN EMBRYO'S EARLIEST STAGE YET

被引：5

作者：

Subbaraman, Nidhi

机构：

来源：

NATURE | 2021年 / 591卷 / 7851期

关键词：

Stem cells; Developmental biology; Cell biology; Biochemistry;

D O I：

10.1038/d41586-021-00695-8

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The experiments use human cells to imitate the blastocyst phase — offering a crucial window into human development.

引用

页码：510 / 511

页数：3

共 7 条

[1]

Fan Y., 2021, PREPRINT BIORXIV, DOI [10.1101/2021.03.09.434313, DOI 10.1101/2021.03.09.434313]

[2] Modelling human blastocysts by reprogramming fibroblasts into iBlastoids [J].

Liu, Xiaodong ;

Tan, Jia Ping ;

Schroder, Jan ;

Aberkane, Asma ;

Ouyang, John F. ;

Mohenska, Monika ;

Lim, Sue Mei ;

Sun, Yu B. Y. ;

Chen, Joseph ;

Sun, Guizhi ;

Zhou, Yichen ;

Poppe, Daniel ;

Lister, Ryan ;

Clark, Amander T. ;

Rackham, Owen J. L. ;

Zenker, Jennifer ;

Polo, Jose M. .

NATURE, 2021, 591 (7851) :627-+

[3] An in vitro model of early anteroposterior organization during human development [J].

Moris, Naomi ;

Anlas, Kerim ;

van den Brink, Susanne C. ;

Alemany, Anna ;

Schroeder, Julia ;

Ghimire, Sabitri ;

Balayo, Tina ;

van Oudenaarden, Alexander ;

Arias, Alfonso Martinez .

NATURE, 2020, 582 (7812) :410-+

[4] Blastocyst-like structures generated solely from stem cells [J].

Rivron, Nicolas C. ;

Frias-Aldeguer, Javier ;

Vrij, Erik J. ;

Boisset, Jean-Charles ;

Korving, Jeroen ;

Vivie, Judith ;

Truckenmuller, Roman K. ;

van Oudenaarden, Alexander ;

van Blitterswijk, Clemens A. ;

Geijsen, Niels .

NATURE, 2018, 557 (7703) :106-+

[5]

Sozen B., 2021, PREPRINT BIORXIV, DOI [10.1101/2021.03.12.435175, DOI 10.1101/2021.03.12.435175]

[6] Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid [J].

Sozen, Berna ;

Cox, Andy L. ;

De Jonghe, Joachim ;

Bao, Min ;

Hollfelder, Florian ;

Glover, David M. ;

Zernicka-Goetz, Magdalena .

DEVELOPMENTAL CELL, 2019, 51 (06) :698-+

[7] Blastocyst-like structures generated from human pluripotent stem cells [J].

Yu, Leqian ;

Wei, Yulei ;

Duan, Jialei ;

Schmitz, Daniel A. ;

Sakurai, Masahiro ;

Wang, Lei ;

Wang, Kunhua ;

Zhao, Shuhua ;

Hon, Gary C. ;

Wu, Jun .

NATURE, 2021, 591 (7851) :620-+

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