Assessing Bioresorbable Coronary Devices Methods and Parameters

被引:59
作者
Garcia-Garcia, Hector M. [1 ]
Serruys, Patrick W. [1 ]
Campos, Carlos M. [1 ,2 ]
Muramatsu, Takashi [1 ]
Nakatani, Shimpei [1 ]
Zhang, Yao-Jun [1 ]
Onuma, Yoshinobu [1 ]
Stone, Gregg W. [3 ,4 ]
机构
[1] Erasmus, Thoraxctr, Rotterdam, Netherlands
[2] Univ Sao Paulo, Sch Med, Heart Inst InCor, Sao Paulo, Brazil
[3] Columbia Univ, Med Ctr, New York, NY USA
[4] Cardiovasc Res Fdn, New York, NY USA
关键词
bioresorbable scaffolds; coronary; imaging; intravascular ultrasound; multislice computed tomography; optical coherence tomography; OPTICAL COHERENCE TOMOGRAPHY; FRACTIONAL FLOW RESERVE; MULTI-IMAGING MODALITY; BACKSCATTER INTRAVASCULAR ULTRASOUND; ELUTING STENT IMPLANTATION; 1-YEAR FOLLOW-UP; VASCULAR SCAFFOLD; ARTERY-DISEASE; BLOOD-FLOW; TISSUE CHARACTERIZATION;
D O I
10.1016/j.jcmg.2014.06.018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bioresorbable vascular scaffolds (BRS) represent a novel approach to provide transient vessel support to drug-delivery capability without the long-term limitations of metallic drug-eluting stents (DES). The technology has the potential to overcome many of the safety concerns associated with metallic DES and possibly even convey further clinical benefit. In particular, the BRS are designed to provide short-term lumen support, and after being completely bioresorbed, eliminate the permanent caging typical of metallic DES. However, this technology has required new imaging modalities and methodologies for its assessment because the design, degradation rate, loss of mechanical property, and drug deliverability may affect its safety and efficacy. We provide an overview of all existing methods for assessing bioresorbable devices, from noninvasive to invasive, from light to sound based, and from morphological to functional parameters. (C) 2014 by the American College of Cardiology Foundation.
引用
收藏
页码:1130 / 1148
页数:19
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