Arisandilactone A, a New Triterpenoid from the Fruits of Schisandra arisanensis

被引：27

作者：

Cheng, Yuan-Bin ^{[1
]}

Liao, Tzu-Ching ^{[1
]}

Lo, I-Wen ^{[1
]}

Chen, Yu-Chen ^{[1
]}

Kuo, Yuh-Chi ^{[2
]}

Chen, Shun-Ying ^{[3
]}

Chien, Ching-Te ^{[3
]}

Shen, Ya-Ching ^{[1
]}

机构：

[1] Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 10764, Taiwan

[2] Fu Jen Catholic Univ, Dept Life Sci, Taipei Hsien, Taiwan

[3] Taiwan Forestry Res Inst, Div Silviculture, Taipei, Taiwan

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 05期

关键词：

LIGNANS; CELLS; NORTRITERPENOIDS;

D O I：

10.1021/ol100024r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A phytochemical investigation of the fruits of Schisandra arisanensis has yielded a novel triterpenoid, arisandilactone A (1). Compound 1 has an unprecedented skeleton having a 5/5/7/5/8/5-fused hexacyclic ring system. The structure of 1 was elucidated by spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. A plausible biosynthetic pathway for 1 is also discussed.

引用

页码：1016 / 1019

页数：4

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