Elevated S100B levels in schizophrenia are associated with insulin resistance

被引：52

作者：

Steiner, J. ^{[1
]}

Walter, M. ^{[1
]}

Guest, P. ^{[2
]}

Myint, A. M. ^{[3
]}

Schiltz, K. ^{[1
]}

Panteli, B. ^{[1
]}

Brauner, M. ^{[1
]}

Bernstein, H-G ^{[1
]}

Gos, T. ^{[4
]}

Herberth, M. ^{[2
]}

Schroeter, M. L. ^{[5
]}

Schwarz, M. J. ^{[3
]}

Westphal, S. ^{[6
]}

Bahn, S. ^{[2
]}

Bogerts, B. ^{[1
]}

机构：

[1] Univ Magdeburg, Dept Psychiat, D-39106 Magdeburg, Germany

[2] Univ Cambridge, Inst Biotechnol, Cambridge, England

[3] Univ Munich, Dept Psychiat, D-8000 Munich, Germany

[4] Med Univ Gdansk, Inst Forens Med, Gdansk, Poland

[5] Max Planck Inst Human Cognit & Brain Sci, Leipzig, Germany

[6] Univ Magdeburg, Inst Clin Chem Pathobiochem & Metab Med, D-39106 Magdeburg, Germany

来源：

MOLECULAR PSYCHIATRY | 2010年 / 15卷 / 01期

关键词：

S-100; PROTEIN; SERUM;

D O I：

10.1038/mp.2009.87

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3 / 4

页数：2

共 10 条

[1] S-100 PROTEIN IN ADIPOSE-TISSUE [J].

KATO, K ;

SUZUKI, F ;

NAKAJIMA, T .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1983, 15 (05) :609-&

[2] A simple, sensitive and widely applicable ELISA for S100B:: Methodological features of the measurement of this glial protein [J].

Leite, Marina Conch ;

Galland, Fabiana ;

Brolese, Giovana ;

Guerra, Maria Cristina ;

Bortolotto, Josiane Woutheres ;

Freitas, Rodrigo ;

Vielra de Almeida, Lucia Maria ;

Gottfried, Carmem ;

Goncalves, Carlos-Alberto .

JOURNAL OF NEUROSCIENCE METHODS, 2008, 169 (01) :93-99

[3] Serum S100B protein is increased in fasting rats [J].

Netto, Cristina B. O. ;

Conte, Sabrina ;

Leite, Marina C. ;

Pires, Caroline ;

Martins, Tiago L. ;

Vidal, Penelope ;

Benfato, Mara S. ;

Giugliani, Roberto ;

Gonçalves, Carlos-Alberto .

ARCHIVES OF MEDICAL RESEARCH, 2006, 37 (05) :683-686

[4] Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF [J].

Rothermundt, M ;

Falkai, P ;

Ponath, G ;

Abel, S ;

Bürkle, H ;

Diedrich, M ;

Hetzel, G ;

Peters, M ;

Siegmund, A ;

Pedersen, A ;

Maier, W ;

Schramm, J ;

Suslow, T ;

Ohrmann, P ;

Arolt, V .

MOLECULAR PSYCHIATRY, 2004, 9 (10) :897-899

[5] Elevated serum levels of the glial marker protein S100B are not specific for schizophrenia or mood disorders [J].

Schroeter, M. L. ;

Steiner, J. .

MOLECULAR PSYCHIATRY, 2009, 14 (03) :235-237

[6] S100B is expressed in, and released from, OLN-93 oligodendrocytes: Influence of serum and glucose deprivation [J].

Steiner, J. ;

Bernstein, H. -G. ;

Bogerts, B. ;

Gos, T. ;

Richter-Landsberg, C. ;

Wunderlich, M. T. ;

Keilhoff, G. .

NEUROSCIENCE, 2008, 154 (02) :496-503

[7] S100B-immunopositive glia is elevated in paranoid as compared to residual schizophrenia: A morphometric study [J].

Steiner, Johann ;

Bernstein, Hans-Gert ;

Bielau, Hendrik ;

Farkas, Nadine ;

Winter, Jana ;

Dobrowolny, Henrik ;

Brisch, Ralf ;

Gos, Tomasz ;

Mawrin, Christian ;

Myint, Aye Mu ;

Bogerts, Bernhard .

JOURNAL OF PSYCHIATRIC RESEARCH, 2008, 42 (10) :868-875

[8] HORMONAL-REGULATION OF ADIPOSE S-100 PROTEIN RELEASE [J].

SUZUKI, F ;

KATO, K ;

NAKAJIMA, T .

JOURNAL OF NEUROCHEMISTRY, 1984, 43 (05) :1336-1341

[9] Metabolic syndrome and schizophrenia [J].

Thakore, JH .

BRITISH JOURNAL OF PSYCHIATRY, 2005, 186 :455-456

[10] Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction [J].

Zhong Zhao ;

Ksiezak-Reding, Hanna ;

Riggio, Silvana ;

Haroutunian, Vahram ;

Pasinetti, Giulio M. .

SCHIZOPHRENIA RESEARCH, 2006, 84 (01) :1-14

← 1 →