Effect of Cannabis Use on Human Immunodeficiency Virus DNA During Suppressive Antiretroviral Therapy

被引:19
作者
Chaillon, Antoine [1 ]
Nakazawa, Masato [1 ]
Anderson, Christy [1 ]
Christensen-Quick, Aaron [1 ]
Ellis, Ronald J. [2 ]
Franklin, Donald [2 ,3 ]
Morris, Sheldon R. [1 ]
Gianella, Sara [1 ]
机构
[1] Univ Calif San Diego, Div Infect Dis & Global Publ Hlth, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
关键词
MSM; cannabis; HIV DNA; cellular transcription; MARIJUANA USE; SUBSTANCE USE; HIV; REPLICATION; PEOPLE; CARE;
D O I
10.1093/cid/ciz387
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cannabis use is frequent among people living with human immunodeficiency virus (HIV) and is associated with reduced systemic inflammation. We observed a faster HIV DNA decay during antiretroviral therapy among cannabis users, compared to those with no drug use. No cannabis effect was observed on cellular HIV RNA transcription.
引用
收藏
页码:140 / 143
页数:4
相关论文
共 22 条
  • [1] [Anonymous], 2017, The Health Effects of Cannabis and Cannabinoids. The Current State of Evidence and Recommendations for Research, DOI DOI 10.17226/24625
  • [2] Neurocognitive Impact of Substance Use in HIV Infection
    Byrd, Desiree A.
    Fellows, Robert P.
    Morgello, Susan
    Franklin, Donald
    Heaton, Robert K.
    Deutsch, Reena
    Atkinson, J. Hampton
    Clifford, David B.
    Collier, Ann C.
    Marra, Christina M.
    Gelman, Benjamin
    McCutchan, J. Allen
    Duarte, Nichole A.
    Simpson, David M.
    McArthur, Justin
    Grant, Igor
    [J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2011, 58 (02) : 154 - 162
  • [3] Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy
    Christensen-Quick, Aaron
    Massanella, Marta
    Frick, Andrew
    Rawlings, Stephen A.
    Spina, Celsa
    Vargas-Meneses, Milenka
    Schrier, Rachel
    Nakazawa, Masato
    Anderson, Christy
    Gianella, Sara
    [J]. JOURNAL OF VIROLOGY, 2019, 93 (13)
  • [4] Cannabinoid Receptor 2-Mediated Attenuation of CXCR4-Tropic HIV Infection in Primary CD4+T Cells
    Costantino, Cristina Maria
    Gupta, Achla
    Yewdall, Alice W.
    Dale, Benjamin M.
    Devi, Lakshmi A.
    Chen, Benjamin K.
    [J]. PLOS ONE, 2012, 7 (03):
  • [5] Effects of Cannabinoids on T-cell Function and Resistance to Infection
    Eisenstein, Toby K.
    Meissler, Joseph J.
    [J]. JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2015, 10 (02) : 204 - 216
  • [6] Cytomegalovirus Replication in Semen Is Associated with Higher Levels of Proviral HIV DNA and CD4+ T Cell Activation during Antiretroviral Treatment
    Gianella, Sara
    Massanella, Marta
    Richman, Douglas D.
    Little, Susan J.
    Spina, Celsa A.
    Vargas, Milenka V.
    Lada, Steven M.
    Daar, Eric S.
    Dube, Michael P.
    Haubrich, Richard H.
    Morris, Sheldon R.
    Smith, Davey M.
    [J]. JOURNAL OF VIROLOGY, 2014, 88 (14) : 7818 - 7827
  • [7] Patterns and correlates of cannabis use among individuals with HIV/AIDS in Maritime Canada
    Harris, Gregory E.
    Dupuis, Lise
    Mugford, Gerald J.
    Johnston, Lynn
    Haase, David
    Page, Ginny
    Haldane, Heather
    Harris, Nicholas
    Midodzi, William K.
    Dow, Gordon
    [J]. CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY, 2014, 25 (01) : E1 - E7
  • [8] Kessler R. C., 1998, International Journal of Methods in Psychiatric Research, V7, P171, DOI [10.1002/mpr.47, DOI 10.1002/MPR.47]
  • [9] Daily Marijuana Use is Associated with Missed Clinic Appointments Among HIV-Infected Persons Engaged in HIV Care
    Kipp, Aaron M.
    Rebeiro, Peter F.
    Shepherd, Bryan E.
    Brinkley-Rubinstein, Lauren
    Turner, Megan
    Bebawy, Sally
    Sterling, Timothy R.
    Hulgan, Todd
    [J]. AIDS AND BEHAVIOR, 2017, 21 (07) : 1996 - 2004
  • [10] High-intensity cannabis use and HIV clinical outcomes among HIV-positive people who use illicit drugs in Vancouver, Canada
    Lake, Stephanie
    Kerr, Thomas
    Capler, Rielle
    Shoveller, Jeannie
    Montaner, Julio
    Milloy, M. -J.
    [J]. INTERNATIONAL JOURNAL OF DRUG POLICY, 2017, 42 : 63 - 70