Alopecia Areata: An Update on Treatment Options for Children

被引:15
作者
Peloquin, Lauren [1 ]
Castelo-Soccio, Leslie [2 ,3 ]
机构
[1] Georgetown Univ, Sch Med, Washington, DC USA
[2] Childrens Hosp Philadelphia, 3401 Civ Ctr Blvd,Wood Ctr Room 3335, Philadelphia, PA 19104 USA
[3] Univ Penn, Perlman Sch Med, 3401 Civ Ctr Blvd,Wood Ctr Room 3335, Philadelphia, PA 19104 USA
关键词
PULSE CORTICOSTEROID-THERAPY; JANUS KINASE INHIBITOR; TRIAMCINOLONE ACETONIDE; CLOBETASOL PROPIONATE; TOPICAL MINOXIDIL; ORAL TOFACITINIB; DOUBLE-BLIND; EFFICACY; SAFETY; METHOTREXATE;
D O I
10.1007/s40272-017-0239-z
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pediatric alopecia areata is a spectrum of autoimmune non-scarring alopecia in which some patients lose small patches of hair from their scalp but others lose more or all of the hair from the scalp and body, including eyebrows and eyelashes. Few studies have looked at therapies for this disorder in children, so much of the data are derived from adult literature and describe off-label use of medication. Generally, topical therapies consisting of topical steroids and topical irritating compounds/contact sensitizers are used. Systemic therapies that block the immune system, including Janus kinase (JAK) inhibitors, have also been used in this disease. This paper reviews the data on therapy for alopecia areata in pediatric patients.
引用
收藏
页码:411 / 422
页数:12
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