Deceptive nasal NK/T-cell lymphoma

被引：7
作者：
Thakur, Jagdeep S. [1 ]
Mahajan, Aditi [1 ]
Saluja, Manika [1 ]
Mohindroo, Narinder K. [1 ]
机构：
[1] Indira Gandhi Med Coll, Dept Otolaryngol Head & Neck Surg ENT, Shimla, HP, India
来源：
TROPICAL DOCTOR | 2017年 / 47卷 / 03期
关键词：
Extranodal NK-T-cell Lymphoma; Nose; Sinusitis; Diagnosis; Fungal pathology; Lethal midline granuloma; NATURAL KILLER/T-CELL; SINONASAL;
D O I：
10.1177/0049475516684088
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Nasal NK/T cell lymphoma is rare and it easily masquerades as chronic rhinosinusitis. It has a very poor prognosis and hence early diagnosis, although difficult, is necessary for better outcome. We present a case of a 30-year-old man who presented with nasal obstruction, facial oedema and crusts. High-resolution computed tomography found soft tissue in all sinuses and the nasal cavity. Endoscopic biopsy revealed necrotic and inflammatory tissue with fungi on culture. A diagnosis of fungal rhinosinusitis was made but the patient did not respond to antifungal drugs. A histopathology review with immunohistochemistry suggested nasal NK/T cell lymphoma. The patient was started on chemotherapy but died within 1 week.
引用
收藏
页码：268 / 271
页数：4
相关论文
共 12 条
  • [1] Epidemiology and Pathogenesis of Nasal NK/T-Cell Lymphoma: A Mini-Review
    Aozasa, Katsuyuki
    Zaki, Mona A. A.
    [J]. THESCIENTIFICWORLDJOURNAL, 2011, 11 : 422 - 428
  • [2] Bacchi CE, 1996, AM J CLIN PATHOL, V105, P230
  • [3] Chan JKC, 2011, ROSAI ACKERMANS SURG, V1, P291
  • [4] Clinicopathologic and Molecular Features of 122 Brazilian Cases of Nodal and Extranodal NK/T-Cell Lymphoma, Nasal Type, With EBV Subtyping Analysis
    Gualco, Gabriela
    Domeny-Duarte, Pollyanna
    Chioato, Lucimara
    Barber, Glen
    Natkunam, Yasodha
    Bacchi, Carlos E.
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (08) : 1195 - 1203
  • [5] Extranodal natural killer/T-cell lymphoma, nasal type: Clinical and computed tomography findings in the head and neck region
    Hung, Liang-Yueh
    Chang, Po-Hung
    Lee, Ta-Jen
    Hsu, Yin-Ping
    Chen, Yi-Wei
    Fu, Chia-Hsiang
    Huang, Chi-Che
    [J]. LARYNGOSCOPE, 2012, 122 (12) : 2632 - 2639
  • [6] Treatment outcome and pattern of failure in 77 patients with sinonasal natural killer/T-cell or T-cell lymphoma
    Li, CC
    Tien, HF
    Tang, JL
    Yao, M
    Chen, YC
    Su, IJ
    Hsu, SM
    Hong, RL
    [J]. CANCER, 2004, 100 (02) : 366 - 375
  • [7] Mitarnun Winyou, 2006, Asian Pac J Cancer Prev, V7, P91
  • [8] Extranodal nasal-type NK/T-cell lymphoma of the palate and paranasal sinuses
    Nikolaos, Nikitakis
    Grigorios, Polyzois
    Konstantinos, Katoumas
    Savvas, Titsinides
    Vassiliki, Zolota
    Alexandra, Sklavounou
    Theodoros, Papadas
    [J]. AMERICAN JOURNAL OF CASE REPORTS, 2012, 13 : 79 - 85
  • [9] Saleh K A, 2011, Med J Malaysia, V66, P160
  • [10] Soon BKH, 2014, SINGAP MED J, V55, pE109, DOI 10.11622/smedj.2013210
12