Cell-penetrating-peptide-coated nanoribbons for intracellular nanocarriers

被引：89

作者：

Lim, Yong-beom

Lee, Eunji

Lee, Myongsoo ^{[1
]}

机构：

[1] Yonsei Univ, Ctr Supramol Nanoassembly, Seoul 120749, South Korea

[2] Yonsei Univ, Dept Chem, Seoul 120749, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 19期

关键词：

beta sheets; fluorescence; intracellular delivery; peptides; self-assembly;

D O I：

10.1002/anie.200604576

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Wrap it up: Nanoribbons coated with cell-penetrating peptides (CPPs) allowed the encapsulation of hydrophobic guest molecules. The nanoassembly internalized into mammalian cells with high efficiency and showed selective intracellular compartmentalization owing to its sensitivity to the solution environment. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：3475 / 3478

页数：4

相关论文

共 30 条

[1] pH as a trigger of peptide β-sheet self-assembly and reversible switching between nematic and isotropic phases [J].

Aggeli, A ;

Bell, M ;

Carrick, LM ;

Fishwick, CWG ;

Harding, R ;

Mawer, PJ ;

Radford, SE ;

Strong, AE ;

Boden, N .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (32) :9619-9628

[2] Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change [J].

Bae, Y ;

Fukushima, S ;

Harada, A ;

Kataoka, K .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (38) :4640-4643

[3]

Bae Y., 2003, ANGEW CHEM, V115, P4788, DOI DOI 10.1002/ange.200250653

[4] Cytochrome display on amyloid fibrils [J].

Baldwin, AJ ;

Bader, R ;

Christodoulou, J ;

MacPhee, CE ;

Dobson, CM ;

Barker, PD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (07) :2162-2163

[5] C-terminal PEG blocks the irreversible step in β-amyloid(10-35) fibrillogenesis [J].

Burkoth, TS ;

Benzinger, TLS ;

Jones, DNM ;

Hallenga, K ;

Meredith, SC ;

Lynn, DG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (30) :7655-7656

[6]

Dolphin G T., 2006, ANGEW CHEM, V118, P2765

[7] Control of amyloid β-peptide protoribril formation by a designed template assembly [J].

Dolphin, GT ;

Dumy, P ;

Garcia, J .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (17) :2699-2702

[8] Mastering molecular matter. Supramolecular architectures by hierarchical self-assembly [J].

Elemans, JAAW ;

Rowan, AE ;

Nolte, RJM .

JOURNAL OF MATERIALS CHEMISTRY, 2003, 13 (11) :2661-2670

[9] A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: Hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice [J].

Ewert, KK ;

Evans, HM ;

Zidovska, A ;

Bouxsein, NF ;

Ahmad, A ;

Safinya, CR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (12) :3998-4006

[10] Antibacterial agents based on the cyclic D,L-α-peptide architecture [J].

Fernandez-Lopez, S ;

Kim, HS ;

Choi, EC ;

Delgado, M ;

Granja, JR ;

Khasanov, A ;

Kraehenbuehl, K ;

Long, G ;

Weinberger, DA ;

Wilcoxen, KM ;

Ghadiri, MR .

NATURE, 2001, 412 (6845) :452-455