Determination of antibiotics in sewage from hospitals, nursery and slaughter house, wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China

被引：283

作者：

Chang, Xiaosong ^{[1
]}

Meyer, Michael T. ^{[2
]}

Liu, Xiaoyun ^{[3
]}

Zhao, Qing ^{[1
]}

Chen, Hao ^{[1
]}

Chen, Ji-an ^{[1
]}

Qiu, Zhiqun ^{[1
]}

Yang, Lan ^{[1
]}

Cao, Jia ^{[4
]}

Shu, Weiqun ^{[1
]}

机构：

[1] Third Mil Med Univ, Sch Mil Prevent Med, Dept Environm Hyg, Chongqing 400038, Peoples R China

[2] US Geol Survey, Lawrence, KS 66049 USA

[3] Ctr Dis Prevent & Control, Lanzhou 730020, Peoples R China

[4] Third Mil Med Univ, Sch Mil Prevent Med, Dept Mil Toxicol, Chongqing 400038, Peoples R China

来源：

ENVIRONMENTAL POLLUTION | 2010年 / 158卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Antibiotics; Solid-phase extraction (SPE); Liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS); Three Gorge Reservoir; China; FLUOROQUINOLONE ANTIBACTERIAL AGENTS; PERSONAL CARE PRODUCTS; ENVIRONMENTAL EXPOSURE; PHARMACEUTICALS; CONTAMINANTS; RESISTANCE; GENOTOXICITY; ELIMINATION; EFFLUENT; BACTERIA;

D O I：

10.1016/j.envpol.2009.12.034

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Sewage samples from 4 hospitals, 1 nursery, 1 slaughter house, 1 wastewater treatment plant and 5 source water samples of Chongqing region of Three Gorge Reservoir were analyzed for macrolide, lincosamide, trimethoprim, fluorouinolone, sulfonamide and tetracycline antibiotics by online solid-phase extraction and liquid chromatography-tandem mass spectrometry. Results showed that the concentration of ofloxacin (OFX) in hospital was the highest among all water environments ranged from 1.660 mu g/L to 4.240 mu g/L and norfloxacin (NOR, 0.136-1.620 mu g/L), ciproflaxacin (CIP, ranged from 0.011 mu g/L to 0.136 mu g/L), trimethoprim (IMP, 0.061-0.174 mu g/L) were commonly detected. Removal range of antibiotics in the wastewater treatment plant was 18-100% and the removal ratio of tylosin, oxytetracycline and tetracycline were 100%. Relatively higher removal efficiencies were observed for tylosin (TYL), oxytetracycline (OXY) and tetracycline (TET)(100%), while lower removal efficiencies were observed for Trimethoprim (IMP, 1%), Epi-iso-chlorotetracycline (EICIC, 18%) and Erythromycin-H2O (ERY-H2O, 24%). Antibiotics were removed more efficiently in primary treatment compared with those in secondary treatment. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1444 / 1450

页数：7

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